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On the mechanism of impaired in vitro generation of 3,5,3'-triiodothyronine from thyroxine in the livers of hypothyroid rats.

作者信息

Balsam A, Sexton F, Ingbar S H

出版信息

Endocrinology. 1979 Nov;105(5):1115-21. doi: 10.1210/endo-105-5-1115.

DOI:10.1210/endo-105-5-1115
PMID:39741
Abstract
摘要

相似文献

1
On the mechanism of impaired in vitro generation of 3,5,3'-triiodothyronine from thyroxine in the livers of hypothyroid rats.
Endocrinology. 1979 Nov;105(5):1115-21. doi: 10.1210/endo-105-5-1115.
2
Observations on the factors that control the generation of triiodothyronine from thyroxine in rat liver and the nature of the defect induced by fasting.关于大鼠肝脏中控制甲状腺素生成三碘甲状腺原氨酸的因素以及禁食所致缺陷性质的观察
J Clin Invest. 1979 Jun;63(6):1145-56. doi: 10.1172/JCI109408.
3
Effects of dietary manipulation on the in vitro generation of 3,5,3'-triiodothyronine from thyroxine in rat liver preparations.饮食调控对大鼠肝脏制剂中甲状腺素体外生成3,5,3'-三碘甲状腺原氨酸的影响。
Life Sci. 1981;28(15-16):1727-36. doi: 10.1016/0024-3205(81)90344-1.
4
The role of sulfhydryl groups on the impaired hepatic 3',3,5-triiodothyronine generation from thyroxine in the hypothyroid, starved, fetal, and neonatal rodent.巯基在甲状腺功能减退、饥饿、胎儿及新生啮齿动物肝脏中甲状腺素生成受损的3',3,5-三碘甲状腺原氨酸过程中的作用
J Clin Invest. 1979 Mar;63(3):516-24. doi: 10.1172/JCI109330.
5
Contribution fron local conversion of thyroxine to 3,5,3'-triiodothyronine to intracellular 3,5,3'-triiodothyronine in several organs in hypothyroid rats at isotope equilibrium.甲状腺功能减退大鼠在同位素平衡状态下，甲状腺素在多个器官局部转化为3,5,3'-三碘甲状腺原氨酸并转变为细胞内3,5,3'-三碘甲状腺原氨酸的作用。
Acta Endocrinol (Copenh). 1982 Nov;101(3):386-96. doi: 10.1530/acta.0.1010386.
6
Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats.抑制垂体甲状腺素向3,5,3'-三碘甲状腺原氨酸的转化可防止甲状腺功能减退大鼠中甲状腺素对促甲状腺激素释放的急性抑制作用。
J Clin Invest. 1979 Jul;64(1):117-28. doi: 10.1172/JCI109430.
7
Iodothyronine metabolism in liver and kidney homogenates from hyperthyroid and hypothyroid rats.甲状腺功能亢进和甲状腺功能减退大鼠肝脏和肾脏匀浆中的碘甲状腺原氨酸代谢
Endocrinology. 1978 Jul;103(1):156-61. doi: 10.1210/endo-103-1-156.
8
Effect of hypothyroidism and hyperthyroidism on triiodothyronine production in perfused rat liver.甲状腺功能减退和甲状腺功能亢进对灌注大鼠肝脏中三碘甲状腺原氨酸生成的影响。
Endocrinology. 1984 Mar;114(3):992-7. doi: 10.1210/endo-114-3-992.
9
[Importance of conversion of thyroxine to triiodothyronine for stimulation of mitochondrial alpha-glycerolphosphate dehydrogenase in rats with hypothyroidism].
Endokrynol Pol. 1980 Mar-Apr;31(2):109-16.
10
[Role of cytosol receptor in the regulation of deiodination of thyroxine to triiodothyronine in the microsomal fraction of rat liver].
Endokrynol Pol. 1980 Jul-Aug;31(4):319-24.

引用本文的文献

1
The effect of bile salts on thyroxine 5'-monodeiodination in rat liver homogenate.
Experientia. 1981 Jun;37(6):601-2. doi: 10.1007/BF01990073.
2
NADPH-dependent generation of a cytosolic dithiol which activates hepatic iodothyronine 5'-deiodinase. Demonstration by alkylation with iodoacetamide.NADPH 依赖的胞质二硫醇生成，该二硫醇可激活肝脏碘甲状腺原氨酸 5'-脱碘酶。通过碘乙酰胺烷基化进行证明。
Biochem J. 1986 Dec 1;240(2):559-66. doi: 10.1042/bj2400559.
3
Properties of cytosolic components activating rat hepatic 5' [corrected]-deiodination in the presence of NADPH.在NADPH存在下激活大鼠肝脏5'-脱碘作用的胞质成分的特性。 （注：原文中“5' [corrected]”推测可能是表述有误，这里按“5'-”翻译）
Biochem J. 1986 Mar 1;234(2):391-8. doi: 10.1042/bj2340391.