Hu Ye, Gao Jiyue, Zhuo Qiping, Liu Huixin, Wang Meiling, Jiang Nina, Wang Xueqing, Wang Kainan, Zhao Zuowei, Li Man
Department of Oncology, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Department of Breast Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
Int J Public Health. 2024 Dec 17;69:1607352. doi: 10.3389/ijph.2024.1607352. eCollection 2024.
The incidence of peripheral arterial disease (PAD) in China is increasing. We aim to conduct a comprehensive analysis of the burden of PAD.
We collected information from 1990 to 2019 in the Global Burden of Disease (GBD 2019) study. Joinpoint regression analysis was used to calculate the annual percentage change (APC). Trends in incidence, mortality and DALYs were forecasted by Bayesian age-period-cohort (BAPC) analysis.
In 2019, the number of new cases and prevalence of PAD in China accounted for nearly a quarter of the global proportion. The age-standardized incidence rate (ASIR) declined after rising until 2005. The age-standardized death rate (ASDR) maintained an upward trend. The DALYs was 0.16 million. Incidence, prevalence and DALYs are predominantly female, except for mortality, which is predominantly male. Smoking predominantly affected males, while hypertension and diabetes had a greater impact on females. By 2030, ASDR is elevated, predominantly in males. ASIR and age-standardized DALY rate decline, predominantly in females.
It is urgent for China to develop strategies based on the specific distribution characteristics of the PAD burden.
中国外周动脉疾病（PAD）的发病率正在上升。我们旨在对PAD的负担进行全面分析。
我们收集了全球疾病负担（GBD 2019）研究中1990年至2019年的信息。采用Joinpoint回归分析计算年度百分比变化（APC）。通过贝叶斯年龄-时期-队列（BAPC）分析预测发病率、死亡率和伤残调整生命年（DALY）的趋势。
2019年，中国PAD的新发病例数和患病率占全球比例近四分之一。年龄标准化发病率（ASIR）在2005年之前上升后下降。年龄标准化死亡率（ASDR）呈上升趋势。DALY为16万。发病率、患病率和DALY主要在女性中较高，除了死亡率主要在男性中较高。吸烟主要影响男性，而高血压和糖尿病对女性的影响更大。到2030年，ASDR升高，主要在男性中。ASIR和年龄标准化DALY率下降，主要在女性中。
中国迫切需要根据PAD负担的具体分布特征制定策略。
