Verta Stephanie, Brambs Christine E, Christmann Corina
Department of Obstetrics and Gynecology, Lucerne Cantonal Hospital, Lucerne, 6000, Switzerland.
Int J Womens Health. 2024 Dec 27;16:2343-2354. doi: 10.2147/IJWH.S492026. eCollection 2024.
Douglas abscesses (DA) involving the ovaries and/or fallopian tubes and tubo-ovarian abscesses (TOA) constitute a very rare finding in virginal females. Underlying conditions are suspected to play a role in their development; often however, the exact pathomechanism remains hypothetical or unknown. We report the case of a 19-year-old virginal female who was referred to our outpatient clinic for further clarification of a 6-month ongoing secondary amenorrhea. In the course of the investigations, a large Douglas abscess with distinctive bilateral salpingitis was diagnosed as an incidental finding in a basically oligosymptomatic patient. Laparoscopic abscess drainage was performed and appropriate antibiotic therapy administered. Intraoperatively collected specimens revealed to be the responsible pathogen and detected foreign body giant cell reaction to intestinal contents on histopathological workup. Retrospectively, a small bowel perforation at the level of the jejunojejunostomy after Roux-en-Y gastric bypass with spillage of intestinal contents and positive cultures for , 6 months prior to her referral, was identified as the triggering event. This case, however unique its pathomechanism may be, demonstrates that a history of intestinal leakage in the context of bowel surgery should be considered a relevant risk factor for the development of DA and TOA in virginal females, even if the primary cause lies several months in the past. It is under these circumstances that the clinical presentation can be atypical and misleading, making it all the more difficult to diagnose. Nonetheless, considering the possibility of this rare condition in light of medical history is crucial.
累及卵巢和/或输卵管的道格拉斯脓肿(DA)以及输卵管卵巢脓肿(TOA)在未婚女性中是非常罕见的发现。潜在病因被怀疑在其发病过程中起作用;然而,确切的发病机制往往仍属假设或未知。我们报告一例19岁未婚女性病例,该患者因持续6个月的继发性闭经前来我院门诊进一步明确诊断。在检查过程中,在一名基本无症状的患者中偶然发现了一个巨大的道格拉斯脓肿,并伴有明显的双侧输卵管炎。进行了腹腔镜脓肿引流并给予了适当的抗生素治疗。术中采集的标本经组织病理学检查显示为致病病原体,并检测到对肠内容物的异物巨细胞反应。回顾性分析发现,该患者在转诊前6个月,因Roux-en-Y胃旁路术后空肠空肠吻合口处小肠穿孔,伴有肠内容物溢出且培养出[具体病原体],这被确定为触发事件。然而,无论该病例的发病机制多么独特,都表明即使主要病因发生在数月之前,肠道手术史导致的肠道渗漏仍应被视为未婚女性发生DA和TOA的相关危险因素。在这种情况下,临床表现可能不典型且具有误导性,使得诊断更加困难。尽管如此,根据病史考虑这种罕见疾病的可能性至关重要。