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颅面裂和眶距增宽症的外科治疗:一项单中心队列研究。

Surgical treatment of craniofacial cleft and orbital hypertelorism: a single-center cohort study.

作者信息

As'adi Kamran, Ahmadi Sayedali, Mirsalehi Marjan

机构信息

Departments of1Plastic and Reconstructive Surgery and.

2Neurosurgery, School of Medicine, Iran University of Medical Sciences, Tehran; and.

出版信息

Neurosurg Focus. 2025 Jan 1;58(1):E4. doi: 10.3171/2024.10.FOCUS24573.

Abstract

OBJECTIVE

Craniofacial clefts, characterized by congenital disruptions in the development of facial and cranial tissues, often present alongside orbital hypertelorism (ORH), an abnormal increase in the interorbital distance. These conditions pose significant challenges in craniofacial surgery due to the complex anatomical and functional considerations involved. This single-center cohort study retrospectively analyzed 22 patients diagnosed with craniofacial cleft syndromes and ORH who were treated at the Craniofacial Centre, Fatima Plastic and Reconstructive Surgery Hospital between July 2016 and October 2023.

METHODS

This study outlines the preoperative evaluations, surgical interventions, and postoperative outcomes of these cases. Surgical techniques varied according to the severity and type of deformity, guided by Tessier's classification system. Procedures included spectacle osteotomy, box osteotomy, and facial bipartition osteotomy, with each approach tailored to address the unique anatomical challenges presented by ORH and associated craniofacial anomalies.

RESULTS

There was a 9% incidence of postoperative infections and a 22.7% incidence of CSF leakage, with a subset of these leading to meningitis. These complications underscore the complexity of managing craniofacial clefts and ORH, highlighting the necessity for meticulous surgical planning and postoperative care.

CONCLUSIONS

Despite the challenges, the study demonstrates that individualized, protocol-driven surgical interventions can achieve significant aesthetic and functional improvements in patients with these congenital anomalies.

摘要

目的

颅面部裂隙以面部和颅骨组织发育的先天性破坏为特征,常伴有眶距增宽(ORH),即眶间距离异常增加。由于涉及复杂的解剖和功能因素,这些情况在颅面外科手术中带来了重大挑战。这项单中心队列研究回顾性分析了2016年7月至2023年10月期间在法蒂玛整形与重建外科医院颅面中心接受治疗的22例被诊断为颅面部裂隙综合征和眶距增宽的患者。

方法

本研究概述了这些病例的术前评估、手术干预和术后结果。手术技术根据畸形的严重程度和类型而有所不同,以泰西埃分类系统为指导。手术包括眼镜式截骨术、盒式截骨术和面部二分截骨术,每种方法都针对眶距增宽和相关颅面异常所带来的独特解剖挑战进行了调整。

结果

术后感染发生率为9%,脑脊液漏发生率为22.7%,其中一部分导致了脑膜炎。这些并发症突显了管理颅面部裂隙和眶距增宽的复杂性,强调了精心手术规划和术后护理的必要性。

结论

尽管存在挑战,但该研究表明,个体化的、遵循方案的手术干预能够在患有这些先天性异常的患者中实现显著的美学和功能改善。

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