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社区居住的中老年人膳食钙摄入量与跌倒风险的关联。

Association of dietary calcium intake with risk of falls in community-dwelling middle-aged and older adults.

作者信息

Asano Kosuke, Kabasawa Keiko, Takachi Ribeka, Sawada Norie, Tsugane Shoichiro, Ito Yumi, Narita Ichiei, Nakamura Kazutoshi, Tanaka Junta

机构信息

Department of General Internal Medicine, Uonuma Kikan Hospital, Niigata, Japan; Department of General Internal Medicine, Katsushika Medical Center, The Jikei University School of Medicine, Tokyo, Japan.

Department of Health Promotion Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

出版信息

J Nutr Health Aging. 2025 Mar;29(3):100465. doi: 10.1016/j.jnha.2024.100465. Epub 2024 Dec 31.

Abstract

OBJECTIVES

Although calcium supplementation is reported to play a role in preventing falls, few studies have examined the relationship between dietary intake of calcium and falls. Therefore, this study investigated the association of calcium intake with falls in community-dwelling adults.

DESIGN

Cross-sectional and longitudinal analyses of a prospective cohort study.

SETTING AND PARTICIPANTS

A 5-year follow-up of a community-based cohort study was conducted with participants aged 40 years or older (mean age, 63.1 years). The cross-sectional and longitudinal analyses included 38,566 and 24,066 participants, respectively.

MEASUREMENTS

Dietary calcium intake was assessed using a validated food frequency questionnaire, with energy adjustment. The outcome was any falls in the preceding year, which were recorded in the self-administered questionnaire. The association of calcium intake with falls was estimated by multivariable logistic regression analysis.

RESULTS

The median intake of dietary calcium was 463 mg/day and 577 mg/day in men and women, respectively. In the cross-sectional analysis, lower intake of dietary calcium was associated with falls. The adjusted odds ratio for falls in the lowest quartile versus the highest quartile was found to be 1.29 (95%CI, 1.16, 1.45) in men and 1.12 (95%CI, 1.01, 1.25) in women. The results of the longitudinal analysis were consistent, with the adjusted odds ratio for falls in the lowest quartile versus the highest quartile being 1.20 (95%CI, 1.04, 1.40) in men and 1.23 (95%CI, 1.09, 1.39) in women.

CONCLUSIONS

Lower intake of dietary calcium was associated with a higher risk of falls. Adequate intake of dietary calcium might help to reduce the occurrence of falls.

摘要

目的

尽管据报道补钙在预防跌倒方面发挥作用,但很少有研究探讨膳食钙摄入量与跌倒之间的关系。因此,本研究调查了社区居住成年人钙摄入量与跌倒之间的关联。

设计

前瞻性队列研究的横断面和纵向分析。

设置与参与者

对一项基于社区的队列研究进行了为期5年的随访,参与者年龄在40岁及以上(平均年龄63.1岁)。横断面和纵向分析分别包括38566名和24066名参与者。

测量

使用经过验证的食物频率问卷评估膳食钙摄入量,并进行能量调整。结局是前一年发生的任何跌倒事件,通过自行填写的问卷记录。通过多变量逻辑回归分析估计钙摄入量与跌倒之间的关联。

结果

男性和女性的膳食钙摄入量中位数分别为463毫克/天和577毫克/天。在横断面分析中,膳食钙摄入量较低与跌倒有关。发现男性中最低四分位数与最高四分位数相比,跌倒的调整后优势比为1.29(95%置信区间,1.16, 1.45),女性为1.12(95%置信区间,1.01, 1.25)。纵向分析结果一致,男性中最低四分位数与最高四分位数相比,跌倒的调整后优势比为1.20(95%置信区间,1.04, 1.40),女性为1.23(95%置信区间,1.09, 1.39)。

结论

膳食钙摄入量较低与跌倒风险较高有关。充足的膳食钙摄入量可能有助于减少跌倒的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de18/12180026/7475fcfc47ce/gr1.jpg

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