Martins Laís Bhering, Gamba Magda, Stubbendorff Anna, Gasser Nathalie, Löbl Laura, Stern Florian, Ericson Ulrika, Marques-Vidal Pedro, Vuilleumier Séverine, Chatelan Angeline
Department of Nutrition and Dietetics, Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Carouge-Geneva, Switzerland.
Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; Graduate School for Health Sciences, University of Bern, Bern, Switzerland.
J Nutr. 2025 Feb;155(2):483-491. doi: 10.1016/j.tjnut.2024.12.012. Epub 2024 Dec 30.
An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases, the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.
This prospective study aimed to evaluate the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.
We analyzed data from the CoLaus/PsyCoLaus cohort study (N = 3866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association among diet adherence, incident cardiovascular events, and all-cause mortality.
During a mean follow-up of 7.9 y (SD: ±2.0 y), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66, 1.17) and 0.70 (95% CI: 0.49, 0.98) for the medium-adherence and high-adherence groups, respectively (P-trend = 0.04). We observed no association between adherence groups and cardiovascular events.
In a Swiss cohort, high adherence to the EAT-Lancet diet is associated with a potential 30% lower risk of overall mortality. However, it is not associated with cardiovascular events.
不健康饮食是包括心血管疾病在内的多种非传染性疾病的主要促成因素，而心血管疾病是全球主要死因。此外，我们的食物系统对环境有重大影响。“柳叶刀饮食委员会”推荐了一种能保护全球环境资源的健康饮食。
这项前瞻性研究旨在评估瑞士队列中遵循“柳叶刀饮食”与心血管事件发生率及全因死亡率之间的关联。
我们分析了CoLaus/PsyCoLaus队列研究的数据（N = 3866）。使用半定量食物频率问卷评估饮食摄入量。根据12种食物成分的推荐摄入量和参考区间计算“柳叶刀饮食”依从性得分，范围为0至39分。参与者根据得分三分位数分为低、中、高依从性组。我们使用Cox比例风险回归来评估饮食依从性、心血管事件发生率和全因死亡率之间的关联。
在平均7.9年（标准差：±2.0年）的随访期间，我们初始样本中的294人（7.6%）发生了首次心血管事件，264人（6.8%）死亡。与低依从性组相比，中依从性组和高依从性组全因死亡率的调整后风险比分别为0.88（95%置信区间：0.66，1.17）和0.70（95%置信区间：0.49，0.98）（P趋势 = 0.04）。我们未观察到依从性组与心血管事件之间存在关联。
在瑞士队列中，高度遵循“柳叶刀饮食”与总体死亡率潜在降低30%相关。然而，它与心血管事件无关。
