Suppr超能文献

[他汀类药物预防和治疗肝细胞癌的策略]

[Strategies of statins for the prevention and treatment of hepatocellular carcinoma].

作者信息

Tong T, Li J F, Shi L Z, Zhang L T

机构信息

The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China.

The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China Department of Hepatology & Infectious Diseases, the First Hospital of Lanzhou University, Lanzhou 730000, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2025 Feb 20;33(2):191-197. doi: 10.3760/cma.j.cn501113-20231207-00269.

Abstract

Hepatocellular carcinoma (HCC) is a kind of malignant tumor with an extremely high morbidity and mortality incidence rate. Although some new progress has been made in recent treatment, the overall prognosis is still poor. Therefore, the prevention and treatment of HCC have important clinical significance. Statin drugs are mainly used for the treatment of hypercholesterolemia and the prevention of cardiovascular and cerebrovascular diseases. In recent years, an increasing number of research results have shown that statins have advantages in preventing the occurrence and improving the prognosis of HCC. This paper reviews the new progress performed in the mechanism of statin drug and the current clinical prevention and treatment for HCC.

摘要

肝细胞癌(HCC)是一种发病率和死亡率极高的恶性肿瘤。尽管近年来治疗方面取得了一些新进展,但总体预后仍然很差。因此,HCC的防治具有重要的临床意义。他汀类药物主要用于治疗高胆固醇血症以及预防心脑血管疾病。近年来,越来越多的研究结果表明,他汀类药物在预防HCC发生和改善其预后方面具有优势。本文综述了他汀类药物作用机制的新进展以及目前HCC的临床防治情况。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验