Kim Do Hyun, Hwang Se Hwan
Department of Otolaryngology-Head and Neck Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
J Rhinol. 2024 Nov;31(3):176-178. doi: 10.18787/jr.2024.00031. Epub 2024 Nov 30.
To evaluate the long-term effects of submucosal Medpor implants in patients with empty nose syndrome (ENS), using the Sinonasal Outcome Test (SNOT) score as a measure of clinical improvement. A comprehensive search of six databases was conducted up to October 2024. The analysis included studies that examined the impact of submucosal Medpor implants on refractory ENS symptoms, as assessed by various symptom-specific questionnaires. Post-intervention SNOT scores were evaluated during follow-up periods of over 12 months, showing a statistically significant improvement in ENS symptoms (standardized mean difference [95% confidence interval]= 1.4676 [1.2067; 1.7285]; I=37.2%). This meta-analysis indicates that submucosal Medpor implantation in patients with ENS is associated with significant long-term improvements in nasal symptoms.
为评估鼻黏膜下Medpor植入物对空鼻症（ENS）患者的长期影响，采用鼻窦结局测试（SNOT）评分作为临床改善的衡量指标。截至2024年10月，对六个数据库进行了全面检索。分析纳入了通过各种症状特异性问卷评估鼻黏膜下Medpor植入物对难治性ENS症状影响的研究。在超过12个月的随访期内评估干预后的SNOT评分，结果显示ENS症状有统计学意义的改善（标准化平均差[95%置信区间]=1.4676[1.2067；1.7285]；I²=37.2%）。这项荟萃分析表明，鼻黏膜下Medpor植入术对ENS患者的鼻部症状有显著的长期改善作用。
