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免疫功能正常成年人的社区获得性人博卡病毒感染

Community-Acquired Human Bocavirus Infection in an Immunocompetent Adult.

作者信息

Usta Oğuz, Çöpür Sidar, Şentürk Evren, Atasoy Çetin, Ergönül Önder

机构信息

Department of Infectious Diseases and Clinical Microbiology, Koç University School of Medicine, İstanbul, Türkiye.

Department of Internal Medicine, Koç University School of Medicine, İstanbul, Türkiye.

出版信息

Infect Dis Clin Microbiol. 2024 Dec 19;6(4):339-342. doi: 10.36519/idcm.2024.372. eCollection 2024 Dec.

DOI:10.36519/idcm.2024.372
PMID:39744661
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11687233/
Abstract

Human bocavirus 1 (HBoV1) is a recognized pathogen in respiratory infections among children; however, its prevalence and clinical implications in immunocompetent adults are unclear. We present a case of HBoV1 infection in a 61-year-old immunocompetent female patient with myositis, leading to respiratory failure. The involvement of respiratory muscles rather than lung parenchyma was observed. By this case, we highlight the importance of HBoV1 infection as a potential cause of viral pneumonia and myositis in adults. Prompt recognition and management of such cases are crucial for optimal patient outcomes and to avoid unnecessary use of antibiotics.

摘要

人博卡病毒1型（HBoV1）是儿童呼吸道感染中一种已被确认的病原体；然而，其在免疫功能正常的成年人中的流行情况及临床意义尚不清楚。我们报告了一例61岁免疫功能正常的女性患者感染HBoV1并伴有肌炎，最终导致呼吸衰竭的病例。观察到呼吸肌受累而非肺实质受累。通过该病例，我们强调了HBoV1感染作为成人病毒性肺炎和肌炎潜在病因的重要性。对此类病例的及时识别和处理对于实现最佳患者预后及避免不必要的抗生素使用至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a237/11687233/c34c77c855ae/IDCM-6-4-372_Figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a237/11687233/f50b6e2e0ce4/IDCM-6-4-372_Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a237/11687233/c34c77c855ae/IDCM-6-4-372_Figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a237/11687233/f50b6e2e0ce4/IDCM-6-4-372_Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a237/11687233/c34c77c855ae/IDCM-6-4-372_Figure2.jpg

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本文引用的文献

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Case Report: Bocavirus Infection Radiologically Resembling a Congestive Heart Failure in a Patient with Metastatic Castration-Resistant Prostate Cancer.病例报告：转移性去势抵抗性前列腺癌患者的博卡病毒感染，影像学上类似于充血性心力衰竭。
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成人博卡病毒感染：临床特征和影像学表现。
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7
Respiratory viruses in bronchoalveolar lavage: a hospital-based cohort study in adults.支气管肺泡灌洗中的呼吸道病毒：一项基于医院的成人队列研究
Thorax. 2009 May;64(5):399-404. doi: 10.1136/thx.2008.105155. Epub 2009 Jan 27.
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Evidence of human bocavirus circulating in children and adults, Cleveland, Ohio.俄亥俄州克利夫兰市儿童和成人中存在人博卡病毒的证据。
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9
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Clin Microbiol Rev. 2008 Jul;21(3):473-94. doi: 10.1128/CMR.00001-08.
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