Harikrishnan Sivadasanpillai, Bahl Ajay, Roy Ambuj, Mishra Animesh, Prajapati Jayesh, Manjunath C N, Sethi Rishi, Guha Santanu, Satheesh Santhosh, Dhaliwal R S, Sharma Meenakshi, Ganapathy Sanjay, Jeemon Panniyammakal
Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India.
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Nat Commun. 2025 Jan 2;16(1):275. doi: 10.1038/s41467-024-55362-z.
Survival outcomes of patients with heart failure (HF) based on their disease etiology are not well described. Here, we provide one-year mortality outcomes of 10850 patients with HF (mean age = 59.9 years, 31% women) in India. Ischemic heart disease (71.9%), dilated cardiomyopathy (17.3), rheumatic heart disease (5.4), non-rheumatic valvular heart disease (1.9), hypertrophic cardiomyopathy (0.8), congenital heart disease (0.7), peri-partum cardiomyopathy (0.5), restrictive cardiomyopathy (0.4), and infective endocarditis (0.1) were the main disease etiologies. Mortality rate per 100-person years of follow-up varied from 13.8 (95% CI: 6.2-30.7) in peri-partum cardiomyopathy to 92.9 (46.5-185.9) in infective endocarditis. Compared to ischemic heart disease, the mortality was two to five times higher in rheumatic heart disease (HR = 2.0; 95% CI: 1.6-2.4), congenital heart disease (2.9; 1.9-4.2), and infective endocarditis (4.8; 2.4-9.8). The wide variations in mortality rate in HF patients may bring possible clinical applicability of risk stratification.
基于病因的心力衰竭（HF）患者的生存结果尚无充分描述。在此，我们提供了印度10850例HF患者（平均年龄59.9岁，31%为女性）的一年死亡率结果。缺血性心脏病（71.9%）、扩张型心肌病（17.3%）、风湿性心脏病（5.4%）、非风湿性瓣膜性心脏病（1.9%）、肥厚型心肌病（0.8%）、先天性心脏病（0.7%）、围产期心肌病（0.5%）、限制性心肌病（0.4%）和感染性心内膜炎（0.1%）是主要病因。每100人年随访的死亡率从围产期心肌病的13.8（95%CI：6.2 - 30.7）到感染性心内膜炎的92.9（46.5 - 185.9）不等。与缺血性心脏病相比，风湿性心脏病（HR = 2.0；95%CI：1.6 - 2.4）、先天性心脏病（2.
