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远端未融合节段的椎间盘退变:Lenke 3c、5c、6c型青少年特发性脊柱侧弯后路融合术后附加现象的原因还是结果?

'Disc degeneration in distal unfused segments: cause or consequence of adding-on after posterior fusion of lenke 3c, 5c, 6c adolescent idiopathic scoliosis?'.

作者信息

Ketenci Ismail Emre, Yanik Hakan Serhat, Marasli Mert Kahraman, Erdem Sevki

机构信息

Department of Orthopaedics & Traumatology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.

出版信息

Acta Neurochir (Wien). 2025 Jan 2;167(1):1. doi: 10.1007/s00701-024-06412-4.

Abstract

BACKGROUND

The aim of this study is to examine the association between adding-on (AO) and disc degeneration(DD) of distal unfused levels in Lenke 3 C, 5 C, 6 C adolescent idiopathic scoliosis (AIS) patients with a follow-up of at least two years by comparing preoperative and postoperative magnetic resonance imaging (MRI).

METHODS

47 AIS patients (32 females and 15 males) with structural thoracolumbar/lumbar (TL/L) curves treated with long segment thoracolumbar fusion were retrospectively evaluated. Patients were divided into two groups according to the occurrence of the AO (AO and Non-AO groups). The unfused discs were graded using the MRI images according to the Pfirrmann grading method. The Scoliosis Research Society-22 (SRS-22) questionnaire and Visuel Analog Scale (VAS) were used to determine clinical outcomes.

RESULTS

The frequency of AO was found to be 29.78%. Postoperative total Pfirrmann score was significantly associated with AO. L5-S1 disc in the AO group had a statistically significant higher Pfirrmann grade than the Non-AO group. No significant association was found between the VAS and SRS-22 scores related to AO, DD or other radiological outcomes.

CONCLUSION

Although patients with AO demonstrated higher postoperative Pfirmann scores, no impact on clinical scores was observed. Furthermore, patients with AO developed significantly higher DD in L5-S1 disc, even if it is not the segment adjacent to the fusion. L5-S1 disc, which is already susceptible to degeneration, was further compromised in the presence of AO.

摘要

背景

本研究旨在通过比较术前和术后的磁共振成像(MRI),研究Lenke 3C、5C、6C型青少年特发性脊柱侧凸(AIS)患者中,附加融合(AO)与至少随访两年的远端未融合节段椎间盘退变(DD)之间的关联。

方法

回顾性评估47例接受长节段胸腰段融合治疗的结构性胸腰段/腰段(TL/L)曲线的AIS患者(32例女性和15例男性)。根据AO的发生情况将患者分为两组(AO组和非AO组)。根据Pfirrmann分级法,使用MRI图像对未融合椎间盘进行分级。采用脊柱侧弯研究学会22项(SRS-22)问卷和视觉模拟量表(VAS)来确定临床结果。

结果

发现AO的发生率为29.78%。术后总Pfirrmann评分与AO显著相关。AO组的L5-S1椎间盘Pfirrmann分级在统计学上显著高于非AO组。未发现与AO、DD或其他影像学结果相关的VAS和SRS-22评分之间存在显著关联。

结论

虽然AO患者术后Pfirrmann评分较高,但未观察到对临床评分有影响。此外,AO患者在L5-S1椎间盘出现了明显更高的DD,即使它不是与融合相邻的节段。L5-S1椎间盘本身就易发生退变,在存在AO的情况下会进一步受损。

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