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Identification of taste cells and reduced taste-related proteins in saliva correlate with the impaired taste sensitivity in long-coronavirus disease.

作者信息

Patel Parul, Jaishankar Shveta, Srinivasan Mythily

机构信息

Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, Indiana, USA.

Department of Oral Pathology, Medicine and Radiology, Indiana University School of Dentistry, Indianapolis, Indiana, USA.

出版信息

Clin Transl Med. 2025 Jan;15(1):e70165. doi: 10.1002/ctm2.70165.

DOI:10.1002/ctm2.70165
PMID:39748191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11695204/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/3a307c293cc6/CTM2-15-e70165-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/9eeb0e1edf9c/CTM2-15-e70165-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/09b304b99369/CTM2-15-e70165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/3a307c293cc6/CTM2-15-e70165-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/9eeb0e1edf9c/CTM2-15-e70165-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/09b304b99369/CTM2-15-e70165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbb/11695204/3a307c293cc6/CTM2-15-e70165-g003.jpg

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Identification of taste cells and reduced taste-related proteins in saliva correlate with the impaired taste sensitivity in long-coronavirus disease.味觉细胞的识别以及唾液中味觉相关蛋白的减少与长新冠病毒疾病中味觉敏感性受损相关。
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本文引用的文献

1
Taste loss in COVID-19 â€" psychophysical evidence supporting a low prevalence.味觉丧失与 COVID-19 â€" 支持低患病率的心理物理学证据。
Rhinology. 2024 Aug 1;62(4):511-512. doi: 10.4193/Rhin24.040.
2
The gustin gene variation at rs2274333 and PROP taster status affect dietary fat perception: a stepwise multiple regression model study. gustin 基因 rs2274333 变异与 PROP 尝味者状态影响膳食脂肪感知：逐步多元回归模型研究。
J Nutr Biochem. 2024 Jun;128:109619. doi: 10.1016/j.jnutbio.2024.109619. Epub 2024 Mar 10.
3
Long-Term Dysfunction of Taste Papillae in SARS-CoV-2.
新型冠状病毒感染中味觉乳头的长期功能障碍
NEJM Evid. 2023 Sep;2(9). doi: 10.1056/evidoa2300046. Epub 2023 Jul 20.
4
Characteristics of Chemosensory Perception in Long COVID and COVID Reinfection.新冠长期感染和新冠再感染中的化学感觉感知特征
J Clin Med. 2023 May 22;12(10):3598. doi: 10.3390/jcm12103598.
5
Long-COVID in patients with a history of mild or asymptomatic SARS-CoV-2 infection: a Nationwide Cohort Study.有 SARS-CoV-2 感染轻症或无症状病史患者的长期 COVID：一项全国性队列研究。
Scand J Prim Health Care. 2022 Sep;40(3):342-349. doi: 10.1080/02813432.2022.2139480. Epub 2022 Oct 31.
6
Distribution of TAS2R38 bitter taste receptor phenotype and haplotypes among COVID-19 patients.TAS2R38 苦味受体表型和单倍型在 COVID-19 患者中的分布。
Sci Rep. 2022 May 5;12(1):7381. doi: 10.1038/s41598-022-10747-2.
7
Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVID.口腔微生物组炎症型失调与 COVID-19 症状持续时间和长新冠有关。
JCI Insight. 2021 Oct 22;6(20):e152346. doi: 10.1172/jci.insight.152346.
8
Validation of the Waterless Empirical Taste Test (WETT).无水经验味觉测试（WETT）的验证。
Behav Res Methods. 2021 Apr;53(2):864-873. doi: 10.3758/s13428-020-01463-8.
9
Hedgehog Signaling Regulates Taste Organs and Oral Sensation: Distinctive Roles in the Epithelium, Stroma, and Innervation.刺猬信号通路调控味觉器官和口腔感觉：在上皮组织、基质组织和神经支配中具有独特的作用。
Int J Mol Sci. 2019 Mar 16;20(6):1341. doi: 10.3390/ijms20061341.
10
Quality assessment of saliva bank samples.唾液库样本的质量评估。
Biopreserv Biobank. 2012 Jun;10(3):282-7. doi: 10.1089/bio.2011.0039.