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乳腺化生性癌包含三种组织学成分:一例病例报告。

Metaplastic carcinoma of the breast containing three histological components: a case report.

作者信息

Liu Huan, Zhao Gang, Fan Zhimin, Wu Di, Qu Fengjiang

机构信息

Breast Surgery Department, General Surgery Center, The First Hospital of Jilin University, Changchun, China.

Emergency Surgery Department, The First Hospital of Jilin University, Changchun, China.

出版信息

Front Oncol. 2024 Dec 19;14:1470986. doi: 10.3389/fonc.2024.1470986. eCollection 2024.

Abstract

Malignant breast tumors mainly arise from the ductal and lobular epithelium, whereas sarcomas, which originate from the stromal tissues of the breast, account for less than 5% of cases. Mostly, these tumors consist of a single tissue type, rendering malignant breast tumors with three distinct tissue types exceedingly rare. We report a unique case of a malignant breast tumor comprising three tissue types: squamous cell carcinoma (approximately 25%), invasive ductal carcinoma (approximately 5%), and fibrosarcoma (approximately 70%). Given the case's rarity, pre-operative imaging and tumor biopsy failed to yield definitive diagnostic information, we detail the patient's clinical and therapeutic process, providing insights for physicians on clinical diagnosis and treatment.

摘要

恶性乳腺肿瘤主要起源于导管和小叶上皮,而起源于乳腺间质组织的肉瘤病例占比不到5%。大多数情况下,这些肿瘤由单一组织类型构成,因此极为罕见地出现包含三种不同组织类型的恶性乳腺肿瘤。我们报告了一例独特的恶性乳腺肿瘤病例,其包含三种组织类型:鳞状细胞癌(约25%)、浸润性导管癌(约5%)和纤维肉瘤(约70%)。鉴于该病例的罕见性,术前影像学检查和肿瘤活检未能提供明确的诊断信息,我们详细介绍了患者的临床和治疗过程,为医生提供临床诊断和治疗方面的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4192/11693695/29b1ad539b41/fonc-14-1470986-g001.jpg

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