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1例良性前列腺增生症接触式激光汽化术后发生骨和淋巴结转移的快速进展性前列腺癌病例。

A case of rapidly progressive prostate cancer with bone and lymph node metastasis after contact laser vaporization for benign prostatic hyperplasia.

作者信息

Muraoka Kei, Fujisaki Akira, Uchida Kosuke, Hakamata Yasuhiro, Kanda Yuka, Sugiura Kota, Yoshida Masashi, Imai Shin, Otsuki Yoshiro, Yoneda Tatsuaki

机构信息

Department of Urology Seirei Hamamatsu General Hospital Hamamatsu Japan.

Department of Pathology Seirei Hamamatsu General Hospital Hamamatsu Japan.

出版信息

IJU Case Rep. 2024 Oct 25;8(1):47-51. doi: 10.1002/iju5.12806. eCollection 2025 Jan.

Abstract

INTRODUCTION

Prostate cancer is incidentally diagnosed in 6%-11% of benign prostatic hyperplasia surgeries.

CASE PRESENTATION

A 79-year-old man was diagnosed with benign prostatic hyperplasia. The prostate volume was 54.5 mL, and the prostate-specific antigen level was 7.121 ng/mL. Magnetic resonance imaging and prostate biopsy were not performed. He then underwent contact laser vaporization of the prostate. After 3 months, gross hematuria occurred, and the prostate-specific antigen level was 62.495 ng/mL. Cystoscopy and magnetic resonance imaging revealed prostate cancer with bladder invasion. Prostate biopsy and transurethral resection were performed, revealing adenocarcinoma with a Gleason score of 5 + 5. The patient was diagnosed with prostate cancer T4N1M1b, and triplet therapy was initiated. After 6 months, the prostate-specific antigen level was 0.037 ng/mL, and the metastases had shrunk.

CONCLUSION

Vaporization for high-grade prostate cancer can lead to rapid progression. Therefore, screening for prostate cancer before benign prostatic hyperplasia surgery is important.

摘要

引言

在6% - 11%的良性前列腺增生手术中会偶然诊断出前列腺癌。

病例介绍

一名79岁男性被诊断为良性前列腺增生。前列腺体积为54.5毫升,前列腺特异性抗原水平为7.121纳克/毫升。未进行磁共振成像和前列腺活检。随后他接受了前列腺接触式激光汽化术。3个月后,出现肉眼血尿,前列腺特异性抗原水平为62.495纳克/毫升。膀胱镜检查和磁共振成像显示前列腺癌侵犯膀胱。进行了前列腺活检和经尿道切除术,结果显示为 Gleason 评分5 + 5的腺癌。该患者被诊断为前列腺癌T4N1M1b,并开始进行三联疗法。6个月后,前列腺特异性抗原水平为0.037纳克/毫升,转移灶缩小。

结论

高级别前列腺癌的汽化术可导致疾病快速进展。因此,在良性前列腺增生手术前筛查前列腺癌很重要。

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