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1例良性前列腺增生症接触式激光汽化术后发生骨和淋巴结转移的快速进展性前列腺癌病例。

A case of rapidly progressive prostate cancer with bone and lymph node metastasis after contact laser vaporization for benign prostatic hyperplasia.

作者信息

Muraoka Kei, Fujisaki Akira, Uchida Kosuke, Hakamata Yasuhiro, Kanda Yuka, Sugiura Kota, Yoshida Masashi, Imai Shin, Otsuki Yoshiro, Yoneda Tatsuaki

机构信息

Department of Urology Seirei Hamamatsu General Hospital Hamamatsu Japan.

Department of Pathology Seirei Hamamatsu General Hospital Hamamatsu Japan.

出版信息

IJU Case Rep. 2024 Oct 25;8(1):47-51. doi: 10.1002/iju5.12806. eCollection 2025 Jan.

DOI:10.1002/iju5.12806
PMID:39749293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11693099/
Abstract

INTRODUCTION

Prostate cancer is incidentally diagnosed in 6%-11% of benign prostatic hyperplasia surgeries.

CASE PRESENTATION

A 79-year-old man was diagnosed with benign prostatic hyperplasia. The prostate volume was 54.5 mL, and the prostate-specific antigen level was 7.121 ng/mL. Magnetic resonance imaging and prostate biopsy were not performed. He then underwent contact laser vaporization of the prostate. After 3 months, gross hematuria occurred, and the prostate-specific antigen level was 62.495 ng/mL. Cystoscopy and magnetic resonance imaging revealed prostate cancer with bladder invasion. Prostate biopsy and transurethral resection were performed, revealing adenocarcinoma with a Gleason score of 5 + 5. The patient was diagnosed with prostate cancer T4N1M1b, and triplet therapy was initiated. After 6 months, the prostate-specific antigen level was 0.037 ng/mL, and the metastases had shrunk.

CONCLUSION

Vaporization for high-grade prostate cancer can lead to rapid progression. Therefore, screening for prostate cancer before benign prostatic hyperplasia surgery is important.

摘要

引言

在6% - 11%的良性前列腺增生手术中会偶然诊断出前列腺癌。

病例介绍

一名79岁男性被诊断为良性前列腺增生。前列腺体积为54.5毫升,前列腺特异性抗原水平为7.121纳克/毫升。未进行磁共振成像和前列腺活检。随后他接受了前列腺接触式激光汽化术。3个月后,出现肉眼血尿,前列腺特异性抗原水平为62.495纳克/毫升。膀胱镜检查和磁共振成像显示前列腺癌侵犯膀胱。进行了前列腺活检和经尿道切除术,结果显示为 Gleason 评分5 + 5的腺癌。该患者被诊断为前列腺癌T4N1M1b,并开始进行三联疗法。6个月后,前列腺特异性抗原水平为0.037纳克/毫升,转移灶缩小。

结论

高级别前列腺癌的汽化术可导致疾病快速进展。因此,在良性前列腺增生手术前筛查前列腺癌很重要。

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本文引用的文献

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Int J Clin Oncol. 2022 Jun;27(6):1077-1083. doi: 10.1007/s10147-022-02156-2. Epub 2022 Mar 25.
2
Photoselective Vaporization of the Prostate in the Management of Lower Urinary Tract Symptoms in Prostate Cancer Patients on Active Surveillance.主动监测前列腺癌患者下尿路症状的经尿道前列腺选择性光汽化治疗。
Urology. 2021 Oct;156:225-230. doi: 10.1016/j.urology.2021.01.040. Epub 2021 Feb 2.
3
GreenLight HPS laser 120 W vs diode laser 300 W vaporization of the prostate for the treatment of benign prostatic hyperplasia in Japanese patients: A prospective, single-center, randomized clinical trial.
绿光高功率半导体激光120W与二极管激光300W汽化治疗日本患者良性前列腺增生症的前瞻性、单中心、随机临床试验
Low Urin Tract Symptoms. 2021 Jan;13(1):31-37. doi: 10.1111/luts.12324. Epub 2020 Jun 9.
4
Comparison of photoselective green light laser vaporisation versus traditional transurethral resection for benign prostate hyperplasia: an updated systematic review and meta-analysis of randomised controlled trials and prospective studies.经尿道选择性绿激光汽化术与传统经尿道前列腺切除术治疗良性前列腺增生症的比较:随机对照试验和前瞻性研究的更新系统评价和荟萃分析。
BMJ Open. 2019 Aug 21;9(8):e028855. doi: 10.1136/bmjopen-2018-028855.
5
Temporal Trend in Incidental Prostate Cancer Detection at Surgery for Benign Prostatic Hyperplasia.良性前列腺增生手术中偶然发现前列腺癌的时间趋势。
Urology. 2018 Dec;122:152-157. doi: 10.1016/j.urology.2018.07.028. Epub 2018 Aug 20.
6
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J Cancer Res Clin Oncol. 2018 Apr;144(4):751-758. doi: 10.1007/s00432-018-2597-5. Epub 2018 Feb 7.
7
Clinical guidelines for male lower urinary tract symptoms and benign prostatic hyperplasia.男性下尿路症状和良性前列腺增生临床指南。
Int J Urol. 2017 Oct;24(10):716-729. doi: 10.1111/iju.13401. Epub 2017 Jul 26.
8
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9
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Eur Urol. 2017 Jul;72(1):14-19. doi: 10.1016/j.eururo.2016.04.031. Epub 2016 May 9.
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Eur Urol. 2015 Jun;67(6):1099-1109. doi: 10.1016/j.eururo.2014.12.038. Epub 2015 Jan 19.