Shprintzen R J, Schwartz R H, Daniller A, Hoch L
Pediatrics. 1985 Mar;75(3):553-61.
Bifid uvula is often regarded as a marker for submucous cleft palate although this relationship has not been fully confirmed. The reason for the tacitly assumed connection between these two anomalies has, in part, been perpetuated by the generally accepted definition of submucous cleft palate as the triad of bifid uvula, notching of the hard palate, and muscular diastasis of the soft palate. Recently, investigations have provided evidence of more subtle manifestations of submucous cleft palate by the use of nasopharyngoscopic examination of the palate and pharynx. It has been determined that submucous cleft palate can occur even when a peroral examination shows an intact uvula. This finding places the "marker" relationship in question. In order to determine the frequency of association between bifid uvula and submucous clefting, a total ascertainment of children with bifid uvula from a suburban pediatric practice was examined nasopharyngoscopically. It was determined that in all but two cases, children with bifid uvula had some or all of the landmarks of submucous cleft palate. Several of the children were found to have velopharyngeal insufficiency and mildly hypernasal speech. This finding prompts caution in the recommendation of adenoidectomy in the presence of bifid uvula.
尽管这种关系尚未得到充分证实,悬雍垂裂常被视为隐性腭裂的一个标志。这两种异常之间默认联系的原因,部分是由于普遍接受的隐性腭裂定义,即由悬雍垂裂、硬腭切迹和软腭肌层分离组成的三联征。最近,通过对腭部和咽部进行鼻咽镜检查,研究提供了隐性腭裂更细微表现的证据。已经确定,即使经口检查显示悬雍垂完整,隐性腭裂也可能发生。这一发现使“标志”关系受到质疑。为了确定悬雍垂裂与隐性腭裂的关联频率,对一家郊区儿科诊所中所有患有悬雍垂裂的儿童进行了鼻咽镜检查。结果发现,除两例以外,所有患有悬雍垂裂的儿童都有隐性腭裂的部分或全部特征。其中一些儿童被发现存在腭咽闭合不全和轻度高鼻音。这一发现提示在存在悬雍垂裂的情况下推荐腺样体切除术时应谨慎。