Int Urogynecol J. 2025 Feb;36(2):265-277. doi: 10.1007/s00192-024-05923-z. Epub 2025 Jan 3.
Female bladder pain syndrome (FBPS), previously known as interstitial cystitis/bladder pain syndrome, is a life-altering and morbid condition that occurs primarily in female patients and can be variable in presentation. Given the absence of pathognomonic symptoms and sensitive diagnostic tests, significant symptomatic overlap with numerous other pelvic conditions (such as pelvic floor tension myalgia or endometriosis) occurring in women makes diagnosis of FBPS challenging. The frequent co-occurrence of FBPS with other pain conditions and functional somatic syndromes further complicates diagnosis and management. The challenges have limited the progress made in understanding the pathophysiology of the condition and improving approaches to treatment and prevention. Improvement in standardization of the terminology used to describe this unique condition is needed to improve the accuracy of diagnosis and the clinical care for affected patients. Given the variability in presentation and the differing definitions for the condition world-wide, the American Urogynecologic Society and the International Urogynecologic Association convened a joint writing group to standardize terminology around common signs and symptoms of the condition and to clarify the diagnosis as it pertains to female patients with the condition. After careful consideration of a broad range of available data and clinical experiences, consensus opinion recommended adopting the term "FBPS" instead of the misleading "interstitial cystitis" to describe a chronic, intermittent condition of at least 3 months' duration affecting women involving symptoms of pain or discomfort localized to the bladder, often with bladder filling, which are not attributed to other pathology. This term will allow clinicians, researchers, and learners alike to standardize their understanding of FBPS.
女性膀胱疼痛综合征(FBPS),以前称为间质性膀胱炎/膀胱疼痛综合征,是一种改变生活且病态的疾病,主要发生在女性患者中,表现形式多样。由于缺乏特异性症状和敏感的诊断测试,女性中与许多其他盆腔疾病(如盆底紧张性肌痛或子宫内膜异位症)存在明显的症状重叠,这使得FBPS的诊断具有挑战性。FBPS与其他疼痛疾病和功能性躯体综合征的频繁共现进一步使诊断和管理复杂化。这些挑战限制了在理解该疾病的病理生理学以及改善治疗和预防方法方面所取得的进展。需要改进用于描述这种独特疾病的术语的标准化,以提高诊断的准确性和对受影响患者的临床护理。鉴于其表现的变异性以及全球对该疾病的不同定义,美国妇科泌尿学会和国际妇科泌尿协会召集了一个联合写作小组,以围绕该疾病的常见体征和症状对术语进行标准化,并阐明与患有该疾病的女性患者相关的诊断。在仔细考虑了广泛的现有数据和临床经验后,共识意见建议采用“FBPS”一词而非具有误导性的“间质性膀胱炎”来描述一种慢性、间歇性疾病,病程至少3个月,影响女性,涉及局限于膀胱的疼痛或不适症状,通常在膀胱充盈时出现,且不归因于其他病理情况。这个术语将使临床医生、研究人员和学习者等对FBPS的理解标准化。