Iida Naoya, Hor Hicham El, Larson Dirk R, Luetmer Marianne T, Laughlin Ruple S, Amadio Peter C
Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Ultrasound Med Biol. 2025 Mar;51(3):592-597. doi: 10.1016/j.ultrasmedbio.2024.12.003. Epub 2025 Jan 2.
Measurement of thenar muscle elasticity by ultrasound shear wave elastography (SWE) may be useful for the diagnosis and evaluation of carpal tunnel syndrome (CTS), but there is a paucity of information on SWE of the thenar muscles in patients with CTS. The purpose of this study was to investigate the elasticity of the thenar muscles in patients with CTS.
Twenty-two adult patients with a referral diagnosis of CTS (27 hands) and 20 healthy volunteers as a control (20 dominant hands) participated in this study. The elastic modulus of the thenar muscles was measured with SWE in two conditions, rest and pinch. The elastic modulus and percent change between the two conditions for each muscle were compared between groups.
The elastic modulus of the abductor pollicis brevis (APB) in the patient group was lower than that in the control group at rest (20.6 ± 5.6 kPa vs. 25.0 ± 8.5 kPa; p = 0.034). However, the elastic modulus (87.9 ± 49.0 kPa vs. 62.5 ± 28.5 kPa; p = 0.044) and percent change (373.3 ± 336.4% vs. 169.2 ± 116.0%; p = 0.006) of the APB in the patient group were higher than those in the control group with pinch. For the opponens pollicis and adductor pollicis, there was no significant difference in the elastic modulus between groups.
Patients with CTS showed differences in SWE of the APB. Future studies need to investigate the accuracy of SWE in diagnosing CTS and assessing prognosis.
通过超声剪切波弹性成像（SWE）测量大鱼际肌弹性可能有助于腕管综合征（CTS）的诊断和评估，但关于CTS患者大鱼际肌SWE的信息较少。本研究的目的是调查CTS患者大鱼际肌的弹性。
22例被转诊诊断为CTS的成年患者（27只手）和20名健康志愿者作为对照组（20只优势手）参与本研究。在休息和捏取两种状态下，用SWE测量大鱼际肌的弹性模量。比较两组间每块肌肉在两种状态下的弹性模量及变化百分比。
患者组在休息时拇短展肌（APB）的弹性模量低于对照组（20.6±5.6kPa对25.0±8.5kPa；p=0.034）。然而，患者组APB在捏取时的弹性模量（87.9±49.0kPa对62.5±28.5kPa；p=0.044）和变化百分比（373.3±336.4%对169.2±116.0%；p=0.006）高于对照组。对于拇对掌肌和拇收肌，两组间弹性模量无显著差异。
CTS患者的APB在SWE方面存在差异。未来研究需要调查SWE在诊断CTS和评估预后方面的准确性。
