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[辐射对大鼠血液白细胞蛋白质及吞噬活性的影响]

[Effect of irradiation on proteins and phagocytic activity of rat blood leukocytes].

作者信息

Naumenko L A, Dokshina G A

出版信息

Radiobiologiia. 1985 Jan-Feb;25(1):99-103.

PMID:3975381
Abstract

The method of chromatography on DEAE-cellulose was used to study the effect of radiation (180.6 mC/kg) on the physicochemical properties of rat leukocyte proteins. The qualitative changes were noted in the protein spectrum of leukocytes which were indicative of the substantial changes in the cell proteins. A fraction was isolated which caused a 44% inhibition of the phagocytic activity of intact leukocytes in vitro.

摘要

采用DEAE - 纤维素柱色谱法研究辐射(180.6 mC/kg)对大鼠白细胞蛋白质理化性质的影响。观察到白细胞蛋白质谱的定性变化,这表明细胞蛋白质发生了显著改变。分离出一个组分,该组分在体外可使完整白细胞的吞噬活性受到44%的抑制。

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