[辐射对大鼠血液白细胞蛋白质及吞噬活性的影响]
[Effect of irradiation on proteins and phagocytic activity of rat blood leukocytes].
作者信息
Naumenko L A, Dokshina G A
出版信息
Radiobiologiia. 1985 Jan-Feb;25(1):99-103.
PMID:3975381
Abstract
The method of chromatography on DEAE-cellulose was used to study the effect of radiation (180.6 mC/kg) on the physicochemical properties of rat leukocyte proteins. The qualitative changes were noted in the protein spectrum of leukocytes which were indicative of the substantial changes in the cell proteins. A fraction was isolated which caused a 44% inhibition of the phagocytic activity of intact leukocytes in vitro.
摘要
采用DEAE - 纤维素柱色谱法研究辐射（180.6 mC/kg）对大鼠白细胞蛋白质理化性质的影响。观察到白细胞蛋白质谱的定性变化，这表明细胞蛋白质发生了显著改变。分离出一个组分，该组分在体外可使完整白细胞的吞噬活性受到44%的抑制。
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