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紫外线照射后供血者血液白细胞吞噬活性的变化。II. 紫外线照射血液自体输血效果的模拟

[Changes in the leukocyte phagocytic activity of donor blood after its UV irradiation. II. Simulation of the effect of the autotransfusion of UV-irradiated blood].

作者信息

Samoĭlova K A, Obolenskaia K D, Freĭdlin I S

出版信息

Tsitologiia. 1987 Sep;29(9):1048-55.

PMID:3433359
Abstract

The UV-irradiated blood of healthy adults was supplemented with non-irradiated blood in the ratio 1:10. The phagocytic activity (PhA) of monocytes and granulocytes was seen to increase markedly in the whole mixture of blood. In this case the rise of PhA was pronounced 1.4-1.7 times as much as in the case of the non-supplemented, directly UV-irradiated blood. The enhancement of PhA depends on its initial level and may occur simultaneously with structural changes of the cell surface components. It seems reasonable to propose that PhA stimulation may be one of the earliest mechanisms in immunocorrection by UV-irradiated blood therapy.

摘要

健康成年人经紫外线照射的血液与未照射的血液按1:10的比例混合。在整个血液混合物中,单核细胞和粒细胞的吞噬活性(PhA)明显增加。在这种情况下,PhA的升高比未补充、直接经紫外线照射的血液显著1.4 - 1.7倍。PhA的增强取决于其初始水平,并且可能与细胞表面成分的结构变化同时发生。提出PhA刺激可能是紫外线照射血液疗法免疫纠正的最早机制之一似乎是合理的。

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