Xu Jiaoxiong, Huang Shengbo, Fu Zhengzheng, Zheng Wen, Luo Wanting, Zhuang Niangqiao, Liu Liuhong, He Renliang, Yang Fang
Department of Dermatology and Burn, Huangpu People's Hospital of Zhongshan, Zhongshan, Guangdong, China.
Department of Dermatology, Dermatology Hospital of Southern Medical University (Guangdong Provincial Dermatology Hospital), Guangzhou, Guangdong, China.
Photodermatol Photoimmunol Photomed. 2025 Jan;41(1):e70005. doi: 10.1111/phpp.70005.
Acne vulgaris (acne) is one of the most common skin diseases with complex pathogenesis. Numerous studies have shown that the microecosystem of sebaceous glands and Cutibacterium acnes play key roles in its pathogenesis. Antibiotics targeting C. acnes have been widely used in acne treatment, but the growing prevalence of antibiotic resistance has become alarming. Further research into the microecosystem of sebaceous glands and the role of specific C. acnes phylotypes in acne pathogenesis has led to a paradigm shift in acne treatment. Currently, non-antibiotic therapies such as light therapy and laser therapy are becoming increasingly popular, opening up new opportunities in acne management.
Studies on the microecosystem of sebaceous glands associated with acne and the effects of light and laser therapies on the microecosystem in acne treatment were retrieved from the PubMed database.
Dysbiosis of the microecosystem of the pilosebaceous unit is closely related to the pathogenesis of acne. Light and laser therapies have an impact on the microecosystem of the pilosebaceous unit in acne treatment.
Light and laser therapies are the popular alternative options in acne treatment. The mechanisms of their effect on the microecosystem of sebaceous glands are not completely clear and require further research, especially for laser therapy.
寻常痤疮是最常见的皮肤病之一，其发病机制复杂。大量研究表明，皮脂腺微生态系统和痤疮丙酸杆菌在其发病机制中起关键作用。针对痤疮丙酸杆菌的抗生素已广泛用于痤疮治疗，但抗生素耐药性的日益普遍已令人担忧。对皮脂腺微生态系统以及特定痤疮丙酸杆菌菌型在痤疮发病机制中的作用的进一步研究导致了痤疮治疗模式的转变。目前，光疗和激光治疗等非抗生素疗法越来越受欢迎，为痤疮管理带来了新机遇。
从PubMed数据库检索与痤疮相关的皮脂腺微生态系统以及光疗和激光治疗对痤疮治疗中微生态系统影响的研究。
毛囊皮脂腺单位微生态失调与痤疮发病机制密切相关。光疗和激光治疗在痤疮治疗中对毛囊皮脂腺单位微生态系统有影响。
光疗和激光治疗是痤疮治疗中受欢迎的替代选择。它们对皮脂腺微生态系统的作用机制尚不完全清楚，需要进一步研究，尤其是激光治疗。
