Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, 1600 NW 10th Ave., Miami, FL, 33136, USA.
Lasers Med Sci. 2024 Sep 28;39(1):245. doi: 10.1007/s10103-024-04196-8.
Acne vulgaris, commonly known as acne, is the most prevalent skin disorder affecting mainly adolescents and young adults, though it can affect people of all ages, making it the most common complaint by patients presenting to a dermatologist. The overactivity of sebaceous glands primarily drives this skin condition due to androgen influence and the presence of Cutibacterium acnes bacteria. Although typically not directly harmful to patient health, acne can be a highly debilitating disease for patients, affecting their self-image and psychosocial well-being. Standard treatments include topical retinoids, benzoyl peroxide, topical antibiotics, and, for more severe cases, systemic antibiotics or isotretinoin, which require prolonged periods of compliance. All these pharmacologic treatments have a risk of side effects ranging from mild ones, like skin irritation and dryness, to severe ones, like depression. Thus, there is a demand for exploring other treatment modalities in treating acne, and laser and light-based therapies have garnered significant interest. This review article will comprehensively assess emerging laser and other light-based therapies that have shown efficacy in treating acne, including the recently FDA-approved 1,726 nm laser.
寻常痤疮，俗称痤疮，是一种最常见的皮肤疾病，主要影响青少年和年轻人，但也可影响所有年龄段的人群，是皮肤科医生最常遇到的患者抱怨。皮脂腺的过度活跃主要是由于雄激素的影响和痤疮丙酸杆菌的存在而导致这种皮肤状况。虽然通常不会直接危害患者的健康，但痤疮可能会对患者造成高度致残的疾病，影响他们的自我形象和社会心理健康。标准治疗包括局部维 A 酸、过氧化苯甲酰、局部抗生素，以及更严重的病例，需要系统使用抗生素或异维 A 酸，这需要长期遵守。所有这些药物治疗都有副作用的风险，从轻度的皮肤刺激和干燥到严重的抑郁。因此，人们需要探索治疗痤疮的其他治疗方式，激光和光基疗法已经引起了极大的关注。这篇综述文章将全面评估新兴的激光和其他光基疗法在治疗痤疮方面的疗效，包括最近获得 FDA 批准的 1726nm 激光。
