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喹啉:下一代杀虫剂、除草剂和肥料的新型解决方案。

Quinoline: A Novel Solution for Next-Generation Pesticides, Herbicides, and Fertilizers.

作者信息

Khan Shahid Ullah, Nawaz Taufiq, Alam Osama, Khan Dilfaraz, Fahad Shah, Saud Shah, Lu Kun

机构信息

Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City and Southwest University, College of Agronomy and Biotechnology, Southwest University, Chongqing, 400715, People's Republic of China.

Dubai Medical College for Girls (DMCG), Dubai, United Arab Emirates.

出版信息

Appl Biochem Biotechnol. 2025 Apr;197(4):2097-2119. doi: 10.1007/s12010-024-05164-2. Epub 2025 Jan 4.

DOI:10.1007/s12010-024-05164-2
PMID:39754687
Abstract

Quinoline is a nitrogen-containing heterocycle compound widely used in the medical industry for its pharmacological properties, such as its antimalarial, antimicrobial, antiparasitic, anti-inflammatory, and anticancer activities. Beyond its medical significance, quinoline shows promising applications in agriculture as a safe and effective pesticide, herbicide, and fertilizer. This review explores the evolution of quinoline research, beginning with its history and synthesis and transitioning to its biological activities and their relevance in agriculture. It then highlights the potential applications of quinoline in modern agriculture, such as pesticides, herbicides, and fertilizers, for increasing crop yields and resilience while reducing crop waste. Moreover, it discusses formulation strategies that can enhance the efficacy of quinoline. Finally, the review addresses potential challenges, such as toxicity and environmental impact, underscoring the need for further research to harness quinoline's full potential in sustainable agriculture.

摘要

喹啉是一种含氮杂环化合物,因其药理特性,如抗疟疾、抗菌、抗寄生虫、抗炎和抗癌活性,而在医药行业得到广泛应用。除了其医学意义外,喹啉作为一种安全有效的杀虫剂、除草剂和肥料,在农业中也显示出有前景的应用。本文综述探讨了喹啉研究的发展历程,从其历史和合成开始,过渡到其生物活性及其在农业中的相关性。然后强调了喹啉在现代农业中的潜在应用,如杀虫剂、除草剂和肥料,以提高作物产量和抗逆性,同时减少作物浪费。此外,还讨论了可以提高喹啉功效的配方策略。最后,该综述探讨了潜在的挑战,如毒性和环境影响,强调需要进一步研究以充分发挥喹啉在可持续农业中的潜力。

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本文引用的文献

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Molecules. 2023 Aug 4;28(15):5880. doi: 10.3390/molecules28155880.
2
A Comprehensive Review on the Biological, Agricultural and Pharmaceutical Properties of Secondary Metabolites Based-Plant Origin.基于植物源次生代谢物的生物、农业和药物特性的综合评述。
Int J Mol Sci. 2023 Feb 7;24(4):3266. doi: 10.3390/ijms24043266.
3
Recent advances in functionalized quinoline scaffolds and hybrids-Exceptional pharmacophore in therapeutic medicine.
功能化喹啉支架及杂化物的最新进展——治疗医学中的特殊药效基团
Front Chem. 2023 Jan 6;10:1074331. doi: 10.3389/fchem.2022.1074331. eCollection 2022.
4
The role of nanoparticles in plant biochemical, physiological, and molecular responses under drought stress: A review.纳米颗粒在干旱胁迫下植物生化、生理和分子反应中的作用:综述
Front Plant Sci. 2022 Nov 24;13:976179. doi: 10.3389/fpls.2022.976179. eCollection 2022.
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Extracellular Metabolites of Heterotrophic : A New Source of Bio-Stimulants for Higher Plants.异养型生物细胞外代谢产物:高等植物生物刺激剂的新来源。
Mar Drugs. 2022 Sep 7;20(9):569. doi: 10.3390/md20090569.
6
Advancements in the synthesis of fused tetracyclic quinoline derivatives.稠合四环喹啉衍生物合成的进展
RSC Adv. 2020 May 27;10(34):19867-19935. doi: 10.1039/d0ra02786c. eCollection 2020 May 26.
7
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RSC Adv. 2020 Jun 2;10(35):20784-20793. doi: 10.1039/d0ra03763j. eCollection 2020 May 27.
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