Trim C M, Gilroy B A
Res Vet Sci. 1985 Jan;38(1):30-4.
The carotid and pulmonary arteries were catheterised in six pigs anaesthetised with thiopentone sodium and halothane. A minimum of five days was allowed to elapse before the investigation. The carotid artery pressure, pulmonary artery pressure, cardiac output, arterial pH, PO2, PCO2, plasma glucose and lactate were measured before and after intravenous injection of xylazine (1 mg kg-1) and ketamine 10 mg kg-1). Complete analgesia was produced for 10 minutes in all pigs but by 25 minutes all animals responded to a painful stimulus. The cardiac output and arterial PO2 were significantly decreased for 30 minutes and 10 minutes, respectively. The total vascular resistance was significantly increased. No statistically significant changes occurred in the other variables measured.
对6只用硫喷妥钠和氟烷麻醉的猪进行颈动脉和肺动脉插管。在研究前至少经过5天。在静脉注射甲苯噻嗪（1毫克/千克）和氯胺酮（10毫克/千克）之前和之后，测量颈动脉压、肺动脉压、心输出量、动脉pH值、氧分压、二氧化碳分压、血浆葡萄糖和乳酸。所有猪均产生了10分钟的完全镇痛效果，但到25分钟时，所有动物对疼痛刺激都有反应。心输出量和动脉氧分压分别在30分钟和10分钟内显著降低。总血管阻力显著增加。所测量的其他变量未发生统计学上的显著变化。
