Forlenza Enrico M, Burnett Robert A, Acuña Alexander J, Levine Brett R, Gililland Jeremy M, Della Valle Craig J
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois; Department of Orthopaedic Surgery, University of Utah, Salt Lake City, Utah.
J Arthroplasty. 2025 Sep;40(9S1):S297-S302.e1. doi: 10.1016/j.arth.2024.12.026. Epub 2025 Jan 3.
Revision of a unicompartmental to a total knee arthroplasty (TKA) is often compared to primary TKA with regard to its technical difficulty and complication rates. We sought to compare medical and surgical complications following revision unicompartmental knee arthroplasty (UKA) to those following primary TKA and aseptic revision TKA.
A national administrative claims database was queried for patients undergoing revision UKA between 2010 and 2019. Patients undergoing revision of a UKA were matched to patients undergoing primary TKA and aseptic revision TKA based on age, sex, Elixhauser Comorbidity Index, payer status, and a history of obesity, osteoporosis, tobacco use, and alcohol use disorder. Revision-free survivorship as well as 2-year and 90-day complication rates were compared. Multivariable logistic regression analysis was performed to determine the independent risk of medical and surgical complications.
A total of 3,924 matched primary TKAs, revision of a failed UKA, and aseptic revision TKA patients were included. Overall survivorship was 96.9% (95% confidence interval [CI] 95.9 to 97.8) for primary TKA, 93.4% (95% CI 92.1 to 94.8) for revision UKA, and 89.8% (95% CI 88.2 to 91.5) for aseptic revision TKA at 2-year follow-up (P < 0.001). At two years, revision UKA patients had higher rates of aseptic loosening (2.2 versus 0.8%, P = 0.004), instability (2.4 versus 0.8%, P = 0.002), and mechanical failures (3.0 versus 1.5%, P = 0.012) than primary TKA patients. The 90-day complication rates were comparable between primary TKA and revision UKA patients (all P > 0.05); the risk of reoperation, acute kidney injury, wound dehiscence, hematoma, and transfusion were all higher in the revision TKA than in the revision UKA cohort (all P < 0.05).
Revision-free survivorship and arthroplasty-related complications at two years following revision UKA are lower than that for primary TKA, but higher than that for aseptic revision TKA, whereas medical complications are similar to those following primary TKA.
单髁膝关节置换术(UKA)翻修为全膝关节置换术(TKA)的技术难度和并发症发生率常与初次TKA相比较。我们旨在比较UKA翻修术后与初次TKA及无菌性TKA翻修术后的医疗和手术并发症。
查询2010年至2019年间接受UKA翻修术患者的国家行政索赔数据库。根据年龄、性别、埃利克斯豪泽合并症指数、支付者状态以及肥胖、骨质疏松、吸烟和酒精使用障碍病史,将接受UKA翻修术的患者与接受初次TKA和无菌性TKA翻修术的患者进行匹配。比较无翻修生存率以及2年和90天的并发症发生率。进行多变量逻辑回归分析以确定医疗和手术并发症的独立风险。
共纳入3924例匹配的初次TKA、UKA翻修失败和无菌性TKA翻修患者。2年随访时,初次TKA的总体生存率为96.9%(95%置信区间[CI]95.9至97.8),UKA翻修为93.4%(95%CI92.1至94.8),无菌性TKA翻修为89.8%(95%CI88.2至91.5)(P<0.001)。两年时,UKA翻修患者的无菌性松动发生率(2.2%对0.8%,P=0.004)、不稳定发生率(2.4%对0.8%,P=0.002)和机械故障发生率(3.0%对1.5%,P=0.012)均高于初次TKA患者。初次TKA和UKA翻修患者的90天并发症发生率相当(所有P>0.05);TKA翻修患者再次手术、急性肾损伤、伤口裂开、血肿和输血的风险均高于UKA翻修队列(所有P<0.05)。
UKA翻修术后两年的无翻修生存率和与关节置换相关的并发症低于初次TKA,但高于无菌性TKA翻修术,而医疗并发症与初次TKA相似。