Restrepo Diego J, Guarin Perez Sergio F, Pumford Andrew D, Bedard Nicholas A, Hannon Charles P, Sierra Rafael J
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
J Arthroplasty. 2025 Apr 12. doi: 10.1016/j.arth.2025.04.023.
Previous studies report high failure rates when unicompartmental arthroplasty (UKA) is revised to another UKA (UKA-to-UKA revision). There are certain indications, such as polyethylene failure or periprosthetic joint infection (PJI), where UKA-to-UKA revision may be considered. The purpose of this study was to compare survivorship and failure rates in patients undergoing UKA-to-UKA revision or UKA to total knee arthroplasty (TKA) conversion for various indications.
We reviewed 230 UKA patients (241 knees), and 94% performed in the medial compartment, who were UKA-to-UKA revision (n = 24) or converted to TKA (n = 217) from 1995 to 2022. There was no difference in the mean age (P = 0.39), mean body mass index (P = 0.82), and sex distribution (P = 0.27) between groups. Indications for converting to TKA included aseptic loosening (37%), adjacent compartment osteoarthritis progression (34%), and unexplained pain (21%). Indications for UKA-to-UKA revision included acute PJI (71%), polyethylene dislocations (12%), and aseptic loosening (12%). Kaplan-Meier survivorship analyses were performed for rerevisions and reoperations and compared between groups.
The 2-year survivorship free of any rerevision after conversion TKA was 96% compared to 75% for UKA-to-UKA revision (P < 0.0001). The most common indications for rerevision after UKA-to-UKA revision were PJI (57%) and polyethylene dislocations (28%) and after TKA conversions were aseptic loosening (41%) and PJI (29%). The 2-year survivorship free of any reoperation after conversion TKA was 92% compared to 69% in the UKA-to-UKA revision group (P < 0.0001). Of the UKA-to-UKA revision cases that were performed for PJI (n = 17), the 2-year survivorship free from all-cause re revision was 67%. Of the patients who underwent rerevision in the UKA-to-UKA revision group, five of seven were ultimately converted to TKA.
The 2-year failure rate was six times higher for UKA-to-UKA revision or than after conversion to TKA. Surgeons should be aware of the high failure rate when counseling patients presenting with complications, where UKA-to-UKA revision may seem to be a potentially less invasive option.
既往研究报道,单髁关节置换术(UKA)翻修为另一例UKA(UKA翻修至UKA)时失败率较高。在某些情况下,如聚乙烯磨损或假体周围关节感染(PJI),可考虑进行UKA翻修至UKA。本研究的目的是比较因各种适应证接受UKA翻修至UKA或UKA转换为全膝关节置换术(TKA)的患者的生存率和失败率。
我们回顾了1995年至2022年期间230例接受UKA手术的患者(241个膝关节),其中94%为内侧间室手术,这些患者接受了UKA翻修至UKA(n = 24)或转换为TKA(n = 217)。两组患者的平均年龄(P = 0.39)、平均体重指数(P = 0.82)和性别分布(P = 0.27)无差异。转换为TKA的适应证包括无菌性松动(37%)、相邻间室骨关节炎进展(34%)和不明原因疼痛(21%)。UKA翻修至UKA的适应证包括急性PJI(71%)、聚乙烯脱位(12%)和无菌性松动(12%)。对再次翻修和再次手术进行Kaplan-Meier生存分析,并在组间进行比较。
转换为TKA后2年无任何再次翻修的生存率为96%,而UKA翻修至UKA为75%(P < 0.0001)。UKA翻修至UKA后再次翻修最常见的适应证是PJI(57%)和聚乙烯脱位(28%),TKA转换后为无菌性松动(41%)和PJI(29%)。转换为TKA后2年无任何再次手术的生存率为92%,而UKA翻修至UKA组为69%(P < 0.0001)。在因PJI进行UKA翻修至UKA的病例(n = 17)中,2年无任何原因再次翻修的生存率为67%。在UKA翻修至UKA组接受再次翻修的患者中,7例中有5例最终转换为TKA。
UKA翻修至UKA的2年失败率比转换为TKA后高6倍。当为出现并发症的患者提供咨询时,外科医生应意识到UKA翻修至UKA的高失败率,因为这似乎是一种潜在的侵入性较小的选择。