Hutton J P, Everett E D
South Med J. 1985 Feb;78(2):189-90. doi: 10.1097/00007611-198502000-00016.
A 60-year-old man had pyogenic meningitis due to Francisella tularensis acquired by tick bite. His disease initially improved but later relapsed after a standard course of streptomycin. Complete resolution resulted from prolonged combined therapy with streptomycin and tetracycline. Successful treatment of acute tularemic meningitis has not previously been reported. Our experience suggests that therapy should include agents that reliably penetrate the CSF, that is, tetracycline or chloramphenicol, for optimal treatment of this rare form of tularemia.
一名60岁男性因被蜱虫叮咬感染土拉弗朗西斯菌而患化脓性脑膜炎。他的病情起初有所改善，但在接受标准疗程的链霉素治疗后病情复发。通过链霉素和四环素的长期联合治疗实现了完全康复。此前尚未有急性兔热病脑膜炎成功治疗的报道。我们的经验表明，治疗应包括能可靠穿透脑脊液的药物，即四环素或氯霉素，以对这种罕见的兔热病形式进行最佳治疗。
