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具有抗菌和抗氧化性能的基于硅烯的量子点纳米复合材料涂层功能性防紫外线纺织品:医疗保健和日常防护的通用解决方案。

Silicene-Based Quantum Dots Nanocomposite Coated Functional UV Protected Textiles With Antibacterial and Antioxidant Properties: A Versatile Solution for Healthcare and Everyday Protection.

作者信息

Das Poushali, Ganguly Sayan, Marvi Parham Khoshbakht, Hassan Shiza, Sherazee Masoomeh, Mahana Mohamed, Shirley Tang Xiaowu, Srinivasan Seshasai, Rajabzadeh Amin Reza

机构信息

School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4L8, Canada.

Department of Chemistry & Waterloo Institute for Nanotechnology (WIN), University of Waterloo, 200 University Ave West, Waterloo, Ontario, N2L 3G1, Canada.

出版信息

Adv Healthc Mater. 2025 Mar;14(6):e2404911. doi: 10.1002/adhm.202404911. Epub 2025 Jan 5.

Abstract

The predominant adverse health effects in care delivery result from hospital-acquired (nosocomial) infections, which impose a substantial financial burden on global healthcare systems. Integrating contact-killing antibacterial action, gas permeability, and antioxidant properties into textile coatings offers a transformative solution, significantly enhancing both medical and everyday protective applications. This study presents an innovative, pollution-free physical compounding method for creating a fluorescent biopolymer composite embedded with silicene-based heteroatom-doped carbon quantum dots for the production of functional textiles. The resulting coated fabric shows superior ultraviolet (UV) protection behavior (UV and UV), thermal stability, breathability, mechanical strength, and antioxidant capabilities as demonstrated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) experiment (>78%) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) ABTS assay (>90%). Rigorous testing against both gram positive and gram negative bacteria confirms that the coated fabric has excellent antibacterial activity. Results from time-dependent antibacterial assays indicate that the nanocomposite can markedly inhibit bacterial proliferation within a few hours. Molecular dynamics modeling, in conjunction with experimental investigations, is employed to elucidate the intermolecular interactions influencing the components of the treated cotton fabrics. The ongoing research can result in the creation of cost-effective smart textile substrates aimed at inhibiting microbial contamination in healthcare and medical applications, possibly rendering them commercially viable.

摘要

医疗服务中主要的不良健康影响源于医院获得性(医院内)感染,这给全球医疗系统带来了巨大的经济负担。将接触杀灭抗菌作用、气体渗透性和抗氧化性能整合到纺织涂层中提供了一种变革性解决方案,显著增强了医疗和日常防护应用。本研究提出了一种创新的、无污染的物理复合方法,用于制备嵌入基于硅烯的杂原子掺杂碳量子点的荧光生物聚合物复合材料,以生产功能性纺织品。通过2,2-二苯基-1-苦基肼基(DPPH)实验(>78%)和2,2'-联氮-双-(3-乙基苯并噻唑啉-6-磺酸)ABTS分析(>90%)表明,所得涂层织物具有优异的紫外线(UV)防护性能(UV和UV)、热稳定性、透气性、机械强度和抗氧化能力。对革兰氏阳性菌和革兰氏阴性菌的严格测试证实,涂层织物具有优异的抗菌活性。时间依赖性抗菌试验结果表明,纳米复合材料能在几小时内显著抑制细菌增殖。结合实验研究,采用分子动力学建模来阐明影响处理后棉织物成分的分子间相互作用。正在进行的研究可能会产生具有成本效益的智能纺织基材,旨在抑制医疗保健和医疗应用中的微生物污染,使其具有商业可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e8a/11874647/ae885d294155/ADHM-14-0-g014.jpg

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