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血红蛋白水平与牙龈黑色素沉着分布及严重程度的关系：一项探索性横断面研究。

Relationship of hemoglobin levels and distribution and severity of gingival melanin pigmentation: An exploratory cross-sectional study.

作者信息

Daniel Riya Achamma, Hr Veena, Basavaraju Suman

机构信息

Department of Dental Surgery, MIOT International, Chennai, India.

Department of Periodontics, K. L. E. Society's Institute of Dental Sciences, Bangalore, India.

出版信息

J Adv Periodontol Implant Dent. 2024 Sep 11;16(2):103-108. doi: 10.34172/japid.2024.020. eCollection 2024.

DOI:10.34172/japid.2024.020
PMID:39758263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11699264/
Abstract

BACKGROUND

Recurrence of gingival pigmentation following depigmentation procedures is common, raising the question of the influence of an underlying cause, if any. Melanin, a non-hemoglobin-derived brown pigment, is the most common endogenous pigment contributing to gingival pigmentation. Hemoglobin derivatives are among the other prime pigments that contribute to gingival color. This exploratory cross-sectional study evaluated the influence of hemoglobin levels on the distribution and severity of gingival melanin pigmentation in periodontitis, gingivitis, and healthy periodontium.

METHODS

Twenty subjects with periodontitis (group 1), gingivitis (group 2), and healthy periodontium (group 3) were recruited in this observational study, totaling 60 subjects. The hemoglobin levels in g/dL and Hedin Melanin Index (HMI-1977) scores were recorded for all subjects, and relevant statistical tests were applied (<0.05).

RESULTS

A negative correlation was observed between the hemoglobin levels and the HMI scores for the whole sample and each group. This correlation was statistically significant for the whole sample and for the gingivitis group in which the correlation was moderate.

CONCLUSION

The inverse and significant relation between the hemoglobin levels and distribution and severity of melanin pigmentation observed for the whole sample and the gingivitis group requires further research and validation to identify and manage the confounding factors in the treatment of gingival pigmentation.

摘要

背景

色素沉着去除术后牙龈色素沉着复发很常见，这引发了是否存在潜在原因及其影响的问题。黑色素是一种非血红蛋白衍生的棕色色素，是导致牙龈色素沉着最常见的内源性色素。血红蛋白衍生物是导致牙龈颜色改变的其他主要色素之一。这项探索性横断面研究评估了血红蛋白水平对牙周炎、牙龈炎和健康牙周组织中牙龈黑色素沉着分布及严重程度的影响。

方法

本观察性研究招募了20名牙周炎患者（第1组）、牙龈炎患者（第2组）和牙周组织健康者（第3组），共60名受试者。记录所有受试者的血红蛋白水平（g/dL）和赫丁黑色素指数（HMI - 1977）评分，并进行相关统计学检验（<0.05）。

结果

在整个样本及每组中，均观察到血红蛋白水平与HMI评分呈负相关。对于整个样本和相关性为中度关联的牙龈炎组，这种相关性具有统计学意义。

结论

在整个样本和牙龈炎组中观察到的血红蛋白水平与黑色素沉着分布及严重程度之间的反向且显著的关系，需要进一步研究和验证，以识别和处理牙龈色素沉着治疗中的混杂因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/5d030634afd8/japid-16-103-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/b88bb4a881ac/japid-16-103-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/09b0b6586093/japid-16-103-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/5d030634afd8/japid-16-103-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/b88bb4a881ac/japid-16-103-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/09b0b6586093/japid-16-103-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/11699264/5d030634afd8/japid-16-103-g003.jpg

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