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脑室内神经节神经母细胞瘤:一名年轻成人罕见肿瘤的不常见部位并文献复习

Intraventricular ganglioneuroblastoma: an uncommon location for a rare tumour in a young adult with review of literature.

作者信息

Patel Tarang, Anandani Garima M, Meena Virendrakumar

机构信息

Department of Pathology, All India Institute of Medical Sciences (AIIMS), Rajkot, Gujarat India.

Department of Radiodiagnosis, Geetanjali Medical College & Hospital, Udaipur, India.

出版信息

Int Cancer Conf J. 2024 Sep 18;14(1):12-16. doi: 10.1007/s13691-024-00726-x. eCollection 2025 Jan.

DOI:10.1007/s13691-024-00726-x
PMID:39758788
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11695542/
Abstract

Ganglioneuroblastoma (GNB) is a rare tumour of neuroectodermal origin consisting of a varying proportion of neuroblasts and ganglion cells. GNB arises from sympathoadrenal tissue usually affecting young children. Very few cases of brain GNB have been reported in the literature. To the best of our knowledge, this is the first-ever reported case of GNB at an intraventricular location in young adults. Because of the rarity of the neoplasm, it might be confused with other tumours of intraventricular location both in radiology and histopathology. We report a very rare case, which was surgically operated on and sent for a frozen section followed by a routine report. The final diagnosis was made by Immunohistochemistry (IHC) study. The patient was treated with further radiotherapy.

摘要

神经母细胞瘤(GNB)是一种罕见的神经外胚层起源肿瘤,由不同比例的神经母细胞和神经节细胞组成。GNB起源于交感肾上腺组织,通常影响幼儿。文献中报道的脑GNB病例非常少。据我们所知,这是首次报道的年轻成年人脑室内发生GNB的病例。由于该肿瘤罕见,在放射学和组织病理学上可能会与其他脑室内肿瘤混淆。我们报告了一例非常罕见的病例,该病例接受了手术治疗,并进行了冰冻切片检查,随后出具了常规报告。最终诊断通过免疫组织化学(IHC)研究确定。患者接受了进一步的放射治疗。

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本文引用的文献

1
Intracranial leptomeningeal CNS ganglioneuroblastoma. First report and review of the literature.颅内软脑膜中枢神经系统节细胞神经母细胞瘤。首例报告及文献复习
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