Patel Tarang, Anandani Garima M, Meena Virendrakumar
Department of Pathology, All India Institute of Medical Sciences (AIIMS), Rajkot, Gujarat India.
Department of Radiodiagnosis, Geetanjali Medical College & Hospital, Udaipur, India.
Int Cancer Conf J. 2024 Sep 18;14(1):12-16. doi: 10.1007/s13691-024-00726-x. eCollection 2025 Jan.
Ganglioneuroblastoma (GNB) is a rare tumour of neuroectodermal origin consisting of a varying proportion of neuroblasts and ganglion cells. GNB arises from sympathoadrenal tissue usually affecting young children. Very few cases of brain GNB have been reported in the literature. To the best of our knowledge, this is the first-ever reported case of GNB at an intraventricular location in young adults. Because of the rarity of the neoplasm, it might be confused with other tumours of intraventricular location both in radiology and histopathology. We report a very rare case, which was surgically operated on and sent for a frozen section followed by a routine report. The final diagnosis was made by Immunohistochemistry (IHC) study. The patient was treated with further radiotherapy.
神经母细胞瘤(GNB)是一种罕见的神经外胚层起源肿瘤,由不同比例的神经母细胞和神经节细胞组成。GNB起源于交感肾上腺组织,通常影响幼儿。文献中报道的脑GNB病例非常少。据我们所知,这是首次报道的年轻成年人脑室内发生GNB的病例。由于该肿瘤罕见,在放射学和组织病理学上可能会与其他脑室内肿瘤混淆。我们报告了一例非常罕见的病例,该病例接受了手术治疗,并进行了冰冻切片检查,随后出具了常规报告。最终诊断通过免疫组织化学(IHC)研究确定。患者接受了进一步的放射治疗。