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老年髋部骨折患者意识模糊和维生素D缺乏的早期筛查:一项降低术后谵妄风险的质量改进举措

Early Screening for Confusion and Vitamin D Deficiency in Elderly Hip Fracture Patients: A Quality Improvement Initiative to Mitigate the Risk of Postoperative Delirium.

作者信息

Younis Zubair, Gurukiran Gurukiran, Abdullah Faliq, Kumar Sairam, Ford David, Hamid Muhammad A, Wani Kubra Farooq

机构信息

Orthopaedics, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.

Orthopaedics and Trauma, Royal Shrewsbury Hospital, Shrewsbury, GBR.

出版信息

Cureus. 2024 Dec 4;16(12):e75099. doi: 10.7759/cureus.75099. eCollection 2024 Dec.

Abstract

Background Postoperative delirium (POD) is a common and debilitating complication in elderly hip fracture patients, associated with significant clinical and functional consequences. Early identification of risk factors, such as cognitive impairment and vitamin D deficiency, is essential to mitigate its impact. However, preoperative screening practices are often inconsistent. This quality improvement initiative aimed to assess and improve compliance with early confusion and vitamin D screening in elderly hip fracture patients, with the goal of facilitating timely interventions to reduce the risk of POD. Methods A two-cycle audit was conducted in the Trauma and Orthopaedics Department at Royal Shrewsbury Hospital. The first cycle (April-June 2023) assessed baseline compliance with confusion (Abbreviated Mental Test Score (AMTS)) and vitamin D screening within 24 hours of admission. Identified barriers informed an intervention consisting of educational sessions, visual prompts, and checklist integration. The second cycle (August-October 2023) evaluated the impact of these measures. Compliance rates, timing of assessments, and prevalence of abnormal biochemical and cognitive screening results were analyzed using Fisher's exact test (p < 0.05). Results Baseline compliance with screening was 27 patients (27%) out of 100, with primary barriers including lack of awareness and logistical challenges. Post-intervention compliance improved significantly for 54 patients (52.4%) out of 103 (p = 0.0003). Screening timeliness also increased, with 45 patients (83.33%) out of 54 screenings completed within 24 hours in cycle 2 compared to 14 patients (51.85%) out of 27 in cycle 1 (p = 0.0039). Biochemical analysis revealed persistently high rates of vitamin D deficiency, underscoring the need for early detection. AMTS scores correlated with abnormal confusion screens but highlighted limitations in cognitive-only assessments. Conclusion This quality improvement (QI) initiative demonstrated the efficacy of targeted interventions in improving screening compliance for confusion and vitamin D deficiency in elderly hip fracture patients. The findings advocate for integrating proactive, dual-focused screening protocols into clinical workflows to address modifiable risk factors for POD. Future research should explore the long-term impact of such measures on POD incidence, recovery trajectories, and functional outcomes while emphasizing the need for sustained adherence to screening protocols.

摘要

背景

术后谵妄(POD)是老年髋部骨折患者常见且致残的并发症,会带来严重的临床和功能后果。早期识别认知障碍和维生素D缺乏等风险因素对于减轻其影响至关重要。然而,术前筛查做法往往不一致。这项质量改进举措旨在评估并提高老年髋部骨折患者早期意识模糊和维生素D筛查的依从性,目标是促进及时干预以降低POD风险。方法:在皇家什鲁斯伯里医院创伤与骨科进行了两轮审核。第一个周期(2023年4月至6月)评估入院24小时内意识模糊(简易精神状态检查表(AMTS))和维生素D筛查的基线依从性。确定的障碍为制定一项包括教育课程、视觉提示和检查表整合的干预措施提供了依据。第二个周期(2023年8月至10月)评估了这些措施的影响。使用Fisher精确检验(p<0.05)分析依从率、评估时间以及生化和认知筛查异常结果的发生率。结果:100名患者中基线筛查依从性为27例(27%),主要障碍包括缺乏认识和后勤挑战。干预后,103名患者中有54例(52.4%)依从性显著提高(p = 0.0003)。筛查及时性也有所提高,第二个周期54次筛查中有45例(83.33%)在24小时内完成,而第一个周期27次筛查中有14例(51.85%)在24小时内完成(p = 0.0039)。生化分析显示维生素D缺乏率持续居高不下,凸显了早期检测的必要性。AMTS评分与意识模糊筛查异常相关,但突出了仅进行认知评估的局限性。结论:这项质量改进(QI)举措证明了针对性干预措施在提高老年髋部骨折患者意识模糊和维生素D缺乏筛查依从性方面的有效性。研究结果主张将积极主动、双重点的筛查方案纳入临床工作流程,以应对POD的可改变风险因素。未来的研究应探讨此类措施对POD发生率、恢复轨迹和功能结局的长期影响,同时强调持续遵守筛查方案的必要性。

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本文引用的文献

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Vitamin D deficiency.维生素D缺乏症
N Engl J Med. 2007 Jul 19;357(3):266-81. doi: 10.1056/NEJMra070553.

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