Clabby Kelsey A, Piazza Yelena, Neychev Vladimir
Surgery, University of Central Florida College of Medicine, Orlando, USA.
Pathology, University of Central Florida College of Medicine, Orlando, USA.
Cureus. 2024 Dec 5;16(12):e75183. doi: 10.7759/cureus.75183. eCollection 2024 Dec.
Sarcoidosis is a multisystem disease process with a bimodal distribution typically affecting African American women and those of Scandinavian descent characterized by noncaseating granulomatous disease. We present a case of a 29-year-old African American male patient who was seen in the clinic for recurrent symptomatic cholelithiasis. He had no past medical history or symptoms besides intermittent postprandial right upper quadrant (RUQ) pain with imaging confirming cholelithiasis. He was taken for elective robotic cholecystectomy, and an intraoperative liver biopsy was performed due to incidentally found widespread miliary liver lesions and an enlarged pericystic lymph node. The pathology from the intraoperative sample showed noncaseating granulomas consistent with sarcoidosis, a rare presentation in both the liver and pericystic lymph node.
结节病是一种多系统疾病过程,具有双峰分布,通常影响非裔美国女性和斯堪的纳维亚血统的人,其特征为非干酪样肉芽肿性疾病。我们报告一例29岁的非裔美国男性患者,该患者因复发性症状性胆石症前来门诊就诊。除了间歇性餐后右上腹(RUQ)疼痛外,他没有既往病史或症状,影像学检查证实患有胆石症。他接受了择期机器人胆囊切除术,由于偶然发现广泛的粟粒性肝脏病变和肿大的胆囊周围淋巴结,术中进行了肝脏活检。术中样本的病理显示非干酪样肉芽肿,与结节病一致,这在肝脏和胆囊周围淋巴结中均为罕见表现。