• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名患有胰岛素诱导性脂肪营养不良的1型糖尿病患者的焦虑和身体形象困扰

Anxiety and Body Image Distress in a Type 1 Diabetes Patient With Insulin-Induced Lipodystrophy.

作者信息

Tahir Maham, Raja Andleeb

机构信息

Emergency Department, Bahria International Hospital, Rawalpindi, PAK.

出版信息

Cureus. 2024 Dec 6;16(12):e75225. doi: 10.7759/cureus.75225. eCollection 2024 Dec.

DOI:10.7759/cureus.75225
PMID:39759721
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11700513/
Abstract

This case report presents a rare instance of a 28-year-old female patient with insulin-induced abdominal lipodystrophy, who presented to the emergency department with symptoms of an anxiety attack triggered by body image distress. She was diagnosed with type 1 diabetes at the age of eight years. For the past 10 years, she has been using insulin glargine and insulin lispro, injecting roughly five times per day. The patient knew the importance of the need to rotate injection sites and injection techniques. She mentioned that she changed her insulin needles every two weeks because she was lazy about it. She also mentioned that she used 4 mm 32G pen needles. Her diabetes was well-controlled, with glycated hemoglobin (HbA1c) levels of 6.5%. Clinical examination revealed a soft swelling with striae on the abdomen (hypogastrium and left iliac fossa). The patient reported repeated insulin injections, both rapid-acting and long-acting, in the same lipodystrophic region because it was less painful and provided easier access to the injection site in public. The patient was known to the emergency department staff due to her repeated visits with symptoms of anxiety. Lipodystrophy is a condition characterized by abnormal fat distribution at insulin injection sites. Insulin-induced lipodystrophy is a known complication of long-term insulin therapy, often leading to local adiposity, metabolic disturbances, and psychological challenges. The report underscores the importance of considering psychological aspects when managing patients with acquired lipodystrophy, highlighting the relationship between fat redistribution and depression in this patient population, who are already at increased risk of mood disorders.

摘要

本病例报告呈现了一例罕见情况,一名28岁女性患者患有胰岛素诱导的腹部脂肪营养不良,因身体形象困扰引发焦虑发作症状而就诊于急诊科。她8岁时被诊断为1型糖尿病。在过去10年里,她一直使用甘精胰岛素和赖脯胰岛素,每天大约注射5次。患者知道轮换注射部位和注射技术的重要性。她提到因为偷懒,她每两周更换一次胰岛素针头。她还提到使用的是4毫米32G的笔式针头。她的糖尿病控制良好,糖化血红蛋白(HbA1c)水平为6.5%。临床检查发现腹部(下腹部和左髂窝)有伴有条纹的柔软肿胀。患者报告称,由于同一脂肪营养不良区域注射时疼痛较轻且在公共场合更容易找到注射部位,她在该区域反复注射速效和长效胰岛素。由于她因焦虑症状多次就诊,急诊科工作人员对该患者很熟悉。脂肪营养不良是一种以胰岛素注射部位脂肪分布异常为特征的病症。胰岛素诱导的脂肪营养不良是长期胰岛素治疗的一种已知并发症,常导致局部肥胖、代谢紊乱和心理挑战。该报告强调了在管理获得性脂肪营养不良患者时考虑心理因素的重要性,突出了该患者群体中脂肪重新分布与抑郁之间的关系,这类患者本身患情绪障碍的风险就更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/8708eb076064/cureus-0016-00000075225-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/095bb8c8fd09/cureus-0016-00000075225-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/5c429fa1764f/cureus-0016-00000075225-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/8708eb076064/cureus-0016-00000075225-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/095bb8c8fd09/cureus-0016-00000075225-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/5c429fa1764f/cureus-0016-00000075225-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e28e/11700513/8708eb076064/cureus-0016-00000075225-i03.jpg

相似文献

1
Anxiety and Body Image Distress in a Type 1 Diabetes Patient With Insulin-Induced Lipodystrophy.一名患有胰岛素诱导性脂肪营养不良的1型糖尿病患者的焦虑和身体形象困扰
Cureus. 2024 Dec 6;16(12):e75225. doi: 10.7759/cureus.75225. eCollection 2024 Dec.
2
Lipodystrophy With an Uncommon Clinical Presentation in a Patient With Insulin-Requiring Type 2 Diabetes Mellitus.一名需要胰岛素治疗的2型糖尿病患者出现罕见临床表现的脂肪营养不良。
Cureus. 2024 Nov 17;16(11):e73835. doi: 10.7759/cureus.73835. eCollection 2024 Nov.
3
Local complications of insulin administration sites and effect on diabetes management.胰岛素注射部位的局部并发症及其对糖尿病管理的影响。
J Clin Nurs. 2022 Sep;31(17-18):2530-2538. doi: 10.1111/jocn.16071. Epub 2021 Oct 8.
4
Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy.1型糖尿病合并获得性全身性脂肪营养不良和胰岛素抵抗:长期瘦素治疗的效果
J Clin Endocrinol Metab. 2008 Jan;93(1):26-31. doi: 10.1210/jc.2007-1856. Epub 2007 Oct 16.
5
Associations of insulin-induced lipodystrophy in children, adolescents, and young adults with type 1 diabetes mellitus using recombinant human insulin: a cross-sectional study.应用重组人胰岛素治疗 1 型糖尿病儿童、青少年和青年发生胰岛素诱导的脂肪营养不良的相关性:一项横断面研究。
J Pediatr Endocrinol Metab. 2021 Mar 4;34(4):503-508. doi: 10.1515/jpem-2020-0556. Print 2021 Apr 27.
6
[Lipoatrophy after use of long acting insulin glargine analogue in a 32-year-old patient with type 1 diabetes].[一名32岁1型糖尿病患者使用长效甘精胰岛素类似物后出现脂肪萎缩]
Pediatr Endocrinol Diabetes Metab. 2008;14(1):61-3.
7
A YOUNG ADULT WITH GENERALIZED LIPODYSTROPHY AND DIABETES MELLITUS (CASE REPORT).一名患有全身性脂肪营养不良和糖尿病的年轻成年人(病例报告)。
Georgian Med News. 2018 Apr(277):27-31.
8
Lipodystrophy reactions to insulin: effects of continuous insulin infusion and new insulin analogs.胰岛素所致脂肪营养不良反应:持续胰岛素输注及新型胰岛素类似物的影响
Am J Clin Dermatol. 2007;8(1):21-8. doi: 10.2165/00128071-200708010-00003.
9
Metreleptin Supplementation for Improving Lipid and Glycemic Profiles in Acquired Diabetes Lipodystrophy: A Case Report.补充米泊明改善获得性糖尿病性脂肪营养不良的血脂和血糖谱:病例报告
J Endocr Soc. 2019 Sep 16;3(11):2179-2183. doi: 10.1210/js.2019-00251. eCollection 2019 Nov 1.
10
Acquired Lipodystrophy Associated With Nivolumab in a Patient With Advanced Renal Cell Carcinoma.纳武利尤单抗治疗晚期肾细胞癌相关性获得性脂肪营养不良 1 例
J Clin Endocrinol Metab. 2019 Aug 1;104(8):3245-3248. doi: 10.1210/jc.2018-02221.

引用本文的文献

1
Recent advances in phyto- and microorganisms-mediated synthesis of copper nanoparticles and their emerging applications in healthcare, environment, agriculture and food industry.植物和微生物介导合成铜纳米颗粒的最新进展及其在医疗保健、环境、农业和食品工业中的新兴应用。
Bioprocess Biosyst Eng. 2025 Jul 9. doi: 10.1007/s00449-025-03196-4.

本文引用的文献

1
Impact of lipodystrophy on health-related quality of life: the QuaLip study.脂肪营养不良对健康相关生活质量的影响:QuaLip 研究。
Orphanet J Rare Dis. 2024 Jan 5;19(1):10. doi: 10.1186/s13023-023-03004-w.
2
Psychopathological and psychiatric evaluation of patients affected by lipodystrophy.对脂肪营养不良患者的精神病理学和精神病学评估。
Eat Weight Disord. 2020 Aug;25(4):991-998. doi: 10.1007/s40519-019-00716-6. Epub 2019 May 29.
3
"We're stuck with what we've got": The impact of lipodystrophy on body image.“我们只能接受现状”:脂肪营养不良对身体形象的影响。
J Clin Nurs. 2018 May;27(9-10):1958-1968. doi: 10.1111/jocn.14342.
4
The Diagnosis and Management of Lipodystrophy Syndromes: A Multi-Society Practice Guideline.脂肪营养不良综合征的诊断与管理:多学会实践指南
J Clin Endocrinol Metab. 2016 Dec;101(12):4500-4511. doi: 10.1210/jc.2016-2466. Epub 2016 Oct 6.
5
Insulin lipodystrophy and lipohypertrophy.胰岛素性脂肪营养不良和脂肪增生。
Indian J Endocrinol Metab. 2013 Jul;17(4):773-4. doi: 10.4103/2230-8210.113788.
6
Lipodystrophies: disorders of adipose tissue biology.脂肪营养不良:脂肪组织生物学紊乱。
Biochim Biophys Acta. 2009 Jun;1791(6):507-13. doi: 10.1016/j.bbalip.2008.12.014. Epub 2009 Jan 7.
7
Efficacy of sertraline in a 12-week trial for generalized anxiety disorder.舍曲林在广泛性焦虑症12周试验中的疗效。
Am J Psychiatry. 2004 Sep;161(9):1642-9. doi: 10.1176/appi.ajp.161.9.1642.