Hinojal Isabel, Chimenea Angel, Antiñolo Guillermo, García-Díaz Lutgardo
Department of Obstetrics and Gynecology, Hospital Santa Bárbara, Puertollano, Spain.
Department of Materno-Fetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), Hospital Universitario Virgen del Rocio/CSIC/University of Seville, Avda. Manuel Siurot s/n. ES, Seville, 41013, Spain.
Acta Diabetol. 2025 Jan 6. doi: 10.1007/s00592-024-02439-2.
This study aims to evaluate the impact of continuous glucose monitoring (CGM) on pregnancy outcomes in women with pregestational diabetes mellitus (PGDM).
A retrospective cohort study was conducted on 387 pregnant women with PGDM at Virgen del Rocío University Hospital in Seville, spanning from 2016 to 2022. The patients were categorized into two groups: 212 women who used continuous glucose monitoring (CGM) and 175 women who self-monitoring of blood glucose (SMBG). The study evaluated maternal characteristics, pregnancy complications, delivery methods, neonatal outcomes, and congenital anomalies.
The CGM group exhibited lower weight gain during pregnancy (9.6 kg vs. 10.0 kg, p = 0.02) and required fewer prenatal visits (7 vs. 8, p = 0.01). The rate of cesarean sections was significantly lower in the CGM group (53.1% vs. 58.2%, p = 0.03), and the incidence of macrosomia was reduced (12.9% vs. 22.2%, p = 0.04). There were no significant differences in congenital anomalies, intrauterine fetal deaths, or neonatal deaths between the groups.
CGM in pregnant women with PGDM is associated with better pregnancy outcomes, including reduced cesarean section rates and lower incidence of macrosomia. These findings support the wider implementation of CGM for improved maternal and fetal health in PGDM pregnancies.
本研究旨在评估持续葡萄糖监测（CGM）对孕前糖尿病（PGDM）女性妊娠结局的影响。
对2016年至2022年期间在塞维利亚的罗西奥圣母大学医院就诊的387例PGDM孕妇进行了一项回顾性队列研究。患者分为两组：212例使用持续葡萄糖监测（CGM）的女性和175例自我血糖监测（SMBG）的女性。该研究评估了母亲特征、妊娠并发症、分娩方式、新生儿结局和先天性异常。
CGM组孕期体重增加较低（9.6千克对10.0千克，p = 0.02），产前检查次数较少（7次对8次，p = 0.01）。CGM组剖宫产率显著较低（53.1%对58.2%，p = 0.03），巨大儿发生率降低（12.9%对22.2%，p = 0.04）。两组之间在先天性异常、宫内胎儿死亡或新生儿死亡方面无显著差异。
PGDM孕妇使用CGM与更好的妊娠结局相关，包括剖宫产率降低和巨大儿发生率降低。这些发现支持更广泛地实施CGM以改善PGDM妊娠中的母婴健康。
