Clayton Janine Austin, Bianchi Diana W, Hodes Richard, Schwetz Tara A, Bertagnolli Monica
Office of Research on Women's Health, National Institutes of Health, Bethesda, Maryland.
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
JAMA. 2025 Mar 11;333(10):891-897. doi: 10.1001/jama.2024.25878.
This article highlights key National Institutes of Health (NIH) programs, policies, and scientific advances that have informed and improved the health of women and describe the promise and potential of harnessing cutting-edge science and integrative approaches to advance women's health research. Policy updates combined with recent scientific and programmatic initiatives are intended to expand understanding of women's health, deliver diagnostics, and develop preventive approaches and novel therapies to meet critical health needs of contemporary women.
To benefit all people through the work funded and conducted by the NIH biomedical research enterprise, NIH has implemented policies that broadly expanded the knowledge of human health and disease from the laboratory to the clinic. Historically, women's health research initially focused on reproductive health and female-specific conditions. It has since expanded to encompass all aspects of the health of women. As new knowledge is generated, novel insights are uncovered about how diseases and conditions affect women uniquely, differently, or disproportionately and how sex and gender, as biological and social factors, respectively, influence health and disease at multiple levels. Although cutting-edge research has generated scientific advances leading to lifesaving vaccines, diagnostics, and treatments for women, many still do not have access to them. Thus, the White House announced an initiative that catalyzes innovative, integrative women's health research and propels translation from basic science to practical benefits, improving outcomes for all women across the lifespan.
NIH's policies, programs, and research funding fill gaps in knowledge about the health of women. Their synergistic results generate evidence for data-driven decision-making and targeted interventions that will improve the health not just of women, but of all people.
本文重点介绍了美国国立卫生研究院（NIH）的关键项目、政策和科学进展，这些项目、政策和进展为改善女性健康提供了信息，并描述了利用前沿科学和综合方法推进女性健康研究的前景和潜力。政策更新与近期的科学和项目倡议相结合，旨在扩大对女性健康的理解，提供诊断方法，并开发预防方法和新型疗法，以满足当代女性的关键健康需求。
为了通过NIH生物医学研究企业资助和开展的工作使所有人受益，NIH实施了一系列政策，这些政策广泛地将人类健康和疾病的知识从实验室扩展到了临床。从历史上看，女性健康研究最初侧重于生殖健康和女性特有的疾病。此后，其范围已扩大到涵盖女性健康的各个方面。随着新知识的产生，人们发现了关于疾病和状况如何独特地、不同地或不成比例地影响女性，以及性别作为生物学和社会因素如何在多个层面影响健康和疾病的新见解。尽管前沿研究取得了科学进展，带来了拯救生命的疫苗、诊断方法和治疗方法，但许多女性仍然无法获得这些成果。因此，白宫宣布了一项倡议，以促进创新的、综合的女性健康研究，并推动从基础科学到实际效益的转化，改善所有年龄段女性的健康结果。
NIH的政策、项目和研究资金填补了女性健康知识方面的空白。它们的协同成果为数据驱动的决策和有针对性的干预措施提供了证据，这些措施不仅将改善女性的健康，还将改善所有人的健康。
