Hill M A, Ruth G R, Hilley H D, Torrison J L, Bagent J K, Leman A D
Vet Rec. 1985 Jan 12;116(2):40-7. doi: 10.1136/vr.116.2.40.
The age of onset and morphology of the earliest lesions of dyschondroplasias in pigs have not been established. Bones and growth cartilages from pigs were examined for the presence of lesions using radiological, angiomicrographical and histological techniques. Lesions were in 10 of 11 pigs at 15 days of age and 12 of 21 pigs at one day of age, indicating that the condition was congenital. The simplest and apparently earliest lesion was an area of persistent hypertrophied chondrocytes and matrix which extended from the articular-epiphyseal complex or physis into the epiphysis or metaphysis, respectively. Since the prevalence of lesions was high it was considered that the dyschondroplasia may be part of the usual growth pattern of cartilages in contemporary pigs.
猪软骨发育异常最早病变的发病年龄和形态尚未确定。利用放射学、血管显微镜和组织学技术检查猪的骨骼和生长软骨,以确定是否存在病变。11头15日龄猪中有10头出现病变,21头1日龄猪中有12头出现病变,表明这种情况是先天性的。最简单且显然最早出现的病变是一片持续存在的肥大软骨细胞和基质区域,该区域分别从关节 - 骨骺复合体或生长板延伸至骨骺或干骺端。由于病变的发生率很高,因此认为软骨发育异常可能是当代猪软骨正常生长模式的一部分。