Gökceoğlu Arife Uslu, Taş Nesrin
Alanya Alaaddin Keykubat University, Faculty of Medicine, Department of Pediatric Nephrology, Antalya, Türkiye.
Ankara Training and Research Hospital, Department of Pediatric Nephrology, Ankara, Türkiye.
J Pediatr (Rio J). 2025 May-Jun;101(3):370-374. doi: 10.1016/j.jped.2024.10.011. Epub 2025 Jan 31.
The authors aim to evaluate characteristics of children with fUTI and results of renal bladder ultrasonography (RBUS) and late dimercaptosuccinicacid (DMSA) scan.
This study is designed as retrospective analysis of RBUS and DMSA reports of children with fUTI. Age, gender, number of fUTI, presence of constipation and vesicouretheral reflux (VUR) were recorded.
The study included 160 children with fUTI with a median age of 7 years (6 months 18 years old). The majority of children in this study were girls (86.3 %), older than 60 months (73.1 %) and had one episode of fUTI. The recurrence rates of UTI were similar in both girls and boys. The total rate of constipation was 21.9 %. The rate of renal scarring on DMSA was 16.9 %. The rates of renal scarring were similar at three age groups and both genders. The rate of renal scarring was higher in children with recurrent UTI compared to those with one episode of fUTI (26.4 % and 12.5 %, respectively; p = 0.04). The rate of constipation in children with renal scarring and normal DMSA was similar (p = 0.07). The rate of trabeculation and thick bladder wall was higher in children with renal scarring at DMSA than children with no renal scarring (p = 0.03).
The present study demonstrated that 16.9 % of children with fUTI had renal scarring. The rates of renal scarring were similar in both gender and age groups. Children with recurrent UTI and abnormal bladder results at RBUS had higher rates of renal scarring.
作者旨在评估发热性泌尿道感染（fUTI）患儿的特征以及肾脏膀胱超声检查（RBUS）和延迟二巯基丁二酸（DMSA）扫描的结果。
本研究设计为对fUTI患儿的RBUS和DMSA报告进行回顾性分析。记录年龄、性别、fUTI次数、便秘和膀胱输尿管反流（VUR）的情况。
该研究纳入了160例fUTI患儿，中位年龄为7岁（6个月至18岁）。本研究中的大多数患儿为女孩（86.3%），年龄大于60个月（73.1%），且有过一次fUTI发作。UTI的复发率在女孩和男孩中相似。便秘的总发生率为21.9%。DMSA检查显示的肾瘢痕形成率为16.9%。三个年龄组和两性的肾瘢痕形成率相似。与仅有一次fUTI发作的患儿相比，复发性UTI患儿的肾瘢痕形成率更高（分别为26.4%和12.5%；p = 0.04）。肾瘢痕形成且DMSA结果正常的患儿便秘发生率相似（p = 0.07）。DMSA显示有肾瘢痕形成的患儿小梁形成和膀胱壁增厚的发生率高于无肾瘢痕形成的患儿（p = 0.03）。
本研究表明，16.9%的fUTI患儿有肾瘢痕形成。肾瘢痕形成率在性别和年龄组中相似。RBUS检查膀胱结果异常的复发性UTI患儿肾瘢痕形成率更高。
