Jangir Hemlata, Roy Charli, Goyal Sarvesh, Goindi Achal S, Kedia Shweta, Suri Vaishali
Department of Neuropathology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Childs Nerv Syst. 2025 Jan 6;41(1):84. doi: 10.1007/s00381-024-06743-8.
Cerebral hydatid disease, caused by Echinococcus granulosus, is uncommon in children but presents significant diagnostic challenges due to its potential to mimic malignancy. Only a handful of cases with such a dilemma have been reported yet in the literature. We report a case of a 12-year-old female presenting with progressive headache and seizures, initially suspected to be a pilocytic astrocytoma. However, histopathological evaluation following surgical excision of the lesion rendered an unexpected diagnosis of a cerebral hydatid cyst. This emphasizes the importance of considering parasitic infections in the differential diagnosis of cystic brain lesions, particularly in endemic regions. Surgical removal without rupture is critical to prevent recurrence and complications. This case highlights the need for a thorough understanding of the clinical, imaging, and histopathological assessments to ensure accurate diagnosis and timely appropriate intervention to improve outcomes of such rare intracranial pathologies mimicking malignancy in children.
由细粒棘球绦虫引起的脑包虫病在儿童中并不常见,但由于其可能酷似恶性肿瘤,因此在诊断上面临重大挑战。目前文献中仅报道了少数几例面临这种困境的病例。我们报告一例12岁女性,表现为进行性头痛和癫痫发作,最初怀疑是毛细胞型星形细胞瘤。然而,病变手术切除后的组织病理学评估得出了意外的诊断结果,即脑包虫囊肿。这强调了在囊性脑病变的鉴别诊断中考虑寄生虫感染的重要性,特别是在流行地区。无破裂的手术切除对于预防复发和并发症至关重要。该病例凸显了全面了解临床、影像学和组织病理学评估的必要性,以确保准确诊断并及时进行适当干预,从而改善这类酷似儿童恶性肿瘤的罕见颅内病变的治疗效果。