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儿童颅内包虫囊肿

Intracranial hydatid cysts in children.

作者信息

Erşahin Y, Mutluer S, Güzelbağ E

机构信息

Division of Pediatric Neurosurgery, Ege University Medical School, Izmir, Turkey.

出版信息

Neurosurgery. 1993 Aug;33(2):219-24; discussion 224-5.

PMID:8367043
Abstract

Brain involvement in hydatid disease occurs in 1 to 2% of all Echinococcus granulosus infections. Fifty to 75% of intracranial hydatid cysts are seen in children. This study included 19 children who underwent surgery for intracranial hydatid cysts between January 1979 and September 1992. There were 12 boys and 7 girls, ages 3 to 16 years (mean, 8.1 yr). Headache and vomiting were the predominant symptoms. Papilledema was present in 16 patients, and 2 patients had secondary optic atrophy. A round, cystic lesion without perifocal edema and rim enhancement was detected on the computed tomographic scans of 13 patients. The cystic lesions with rim enhancement and perifocal edema were noted on the computed tomographic scans of 3 patients. Of these three patients, two subsequently had a recurrence. Total removal of the cyst without rupture was achieved in 12 patients. Only a 3-year-old boy in whom the cyst ruptured at surgery died. Seven patients in whom either the hydatid cyst ruptured at surgery or there was systemic hydatid disease received mebendazole therapy. Mebendazole seems to be effective in hydatid disease. Cerebral hydatid cysts should be removed in toto without rupture. The preoperative diagnosis is very important in planning surgery. When a cystic lesion is detected on computed tomographic scan, hydatid disease should be taken into consideration in countries where hydatid disease is endemic.

摘要

脑包虫病在所有细粒棘球绦虫感染中占1%至2%。颅内包虫囊肿50%至75%见于儿童。本研究纳入了19例在1979年1月至1992年9月期间接受颅内包虫囊肿手术的儿童。其中男12例,女7例,年龄3至16岁(平均8.1岁)。头痛和呕吐是主要症状。16例患者出现视乳头水肿,2例患者有继发性视神经萎缩。13例患者的计算机断层扫描显示为圆形囊性病变,无灶周水肿和边缘强化。3例患者的计算机断层扫描显示囊性病变有边缘强化和灶周水肿。这3例患者中有2例随后复发。12例患者实现了囊肿完整切除且未破裂。仅1例3岁男孩在手术中囊肿破裂死亡。7例患者在手术中囊肿破裂或患有全身性包虫病,接受了甲苯咪唑治疗。甲苯咪唑似乎对包虫病有效。脑包虫囊肿应完整切除且不破裂。术前诊断对手术规划非常重要。当计算机断层扫描发现囊性病变时,在包虫病流行地区应考虑到包虫病。

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