弥漫性大B细胞淋巴瘤复发表现为腹壁肌肉无痛性肿块：一例罕见病例报告
Relapse of Diffuse Large B-Cell Lymphoma as Painless Masses in the Abdominal Wall Muscles: A Rare Case Report.
作者信息
Mansour Somar, Abdul Rahman Seif-Aldin, Mansour Majd, Afif Ali, Hasan Raghad, Abdullah Nader, Alshehabi Zuheir
机构信息
Cancer Research Center, Tishreen University Hospital, Latakia, Syria.
Faculty of Medicine, Tishreen University, Latakia, Syria.
出版信息
Cancer Rep (Hoboken). 2025 Jan;8(1):e70114. doi: 10.1002/cnr2.70114.
BACKGROUND
The most frequent type of non-Hodgkin lymphoma (NHL) is diffuse large B-cell lymphoma (DLBCL). Although lymph nodes are the most commonly affected organs compromising 70% of DLBCLs, only 5% of extranodal lymphomas represent skeletal muscle involvement. Specifically, abdominal wall muscle involvement is rare and there are only a few reported cases of DLBCL with this type of muscle involvement. Painful abdominal mass was the main presenting symptom in these reported cases.
CASE
We are reporting a relapsed DLBCL with abdominal wall muscle involvement in a 65-year-old male, presenting with a discomfort and heaviness sensation in the right iliac region with no associated pain.
CONCLUSION
A rare case of DLBCL with recurrence in the abdominal wall muscles as painless masses was reported in this case report. To our knowledge, it is considered the fourth reported in the medical literature. It shows the importance of the diagnostic process that combines imaging with histological examination and immune stains for accurate diagnosis.
背景
非霍奇金淋巴瘤（NHL）最常见的类型是弥漫性大B细胞淋巴瘤（DLBCL）。尽管淋巴结是最常受累的器官，占DLBCL的70%，但仅5%的结外淋巴瘤累及骨骼肌。具体而言，腹壁肌肉受累罕见，仅有少数DLBCL累及此类肌肉的病例报道。在这些报道的病例中，疼痛性腹部肿块是主要的表现症状。
病例
我们报告一例65岁男性复发性DLBCL累及腹壁肌肉，表现为右髂区不适和沉重感，无相关疼痛。
结论
本病例报告了一例罕见的DLBCL复发，表现为腹壁肌肉无痛性肿块。据我们所知，这是医学文献中报道的第四例。它显示了将影像学与组织学检查及免疫染色相结合的诊断过程对于准确诊断的重要性。
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