Westgren M, Dolfin T, Halperin M, Milligan J, Shennan A, Svenningsen N W, Ingemarsson I
Acta Obstet Gynecol Scand. 1985;64(1):51-7. doi: 10.3109/00016348509154688.
In a paired controlled multicenter study of patients in preterm labor of unknown etiology without additional maternal or fetal complications, 59 low birth weight infants in vertex presentation born vaginally were compared with 59 infants delivered by cesarean section. In the early postpartum period, hypothermia and acidosis occurred more often in the vaginal delivery group. The rate of respiratory disorders and need for assisted ventilation did not differ between the groups. Persistent ductus arteriosus occurred in 19% in the vaginal delivery group and in 7% in the abdominal delivery group. At follow-up until 18-24 months of age the rate of cerebral palsy did not differ between the groups, whereas the rate of psychomotor retardation was significantly higher in the vaginal delivery group (p less than 0.05). The difference in percentage of total outcome, i.e. sum of mortality and neurodevelopmental sequelae, being 20.3% in the vaginal delivery group versus 8.5% in the cesarean section group, fails to reach a statistical significance, but the results suggest that for the low birth weight infants, vaginal delivery may be more hazardous than abdominal delivery.
在一项针对病因不明且无其他母体或胎儿并发症的早产患者的配对对照多中心研究中，将59例以头位经阴道分娩的低出生体重婴儿与59例剖宫产分娩的婴儿进行了比较。在产后早期，阴道分娩组体温过低和酸中毒的发生率更高。两组之间呼吸系统疾病的发生率和辅助通气的需求没有差异。动脉导管未闭在阴道分娩组的发生率为19%，在剖宫产组为7%。随访至18 - 24个月龄时，两组之间脑瘫的发生率没有差异，而阴道分娩组精神运动发育迟缓的发生率显著更高（p小于0.05）。总结局（即死亡率和神经发育后遗症的总和）的百分比差异，阴道分娩组为20.3%，剖宫产组为8.5%，未达到统计学显著性，但结果表明，对于低出生体重婴儿，阴道分娩可能比剖宫产更具危险性。
