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胃旁路术后患者的经口内镜下肌切开术,术后贲门失弛缓症管理中的一项治疗挑战

Peroral Endoscopic Myotomy in a Patient With Gastric Bypass, a Therapeutic Challenge in the Management of Postoperative Achalasia.

作者信息

Córdoba Guzmán Andrea Carolina, Fuentes Carlos Fernando, Sabbagh Luis Carlos

机构信息

Departamento de Gastroenterología, Clínica Universitaria Colombia, Grupo Keralty, Bogotá, Colombia.

Departamento de Gastroenterología, Clínica Reina Sofía, Clínica Colsanitas, Grupo Keralty, Bogotá, Colombia.

出版信息

ACG Case Rep J. 2025 Jan 4;12(1):e01584. doi: 10.14309/crj.0000000000001584. eCollection 2025 Jan.

DOI:10.14309/crj.0000000000001584
PMID:39764153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11703431/
Abstract

Achalasia is a rare esophageal motor disorder characterized by incomplete relaxation of the lower esophageal sphincter and ineffective contraction of the esophageal body. This condition is not often associated with obesity; however, in recent years, cases of achalasia after bariatric surgery have been described. We describe the case of a 30-year-old female patient with a history of gastric sleeve surgery in 2018, which, 4 years after the intervention, presented with dysphagia, regurgitation, and weight loss. A diagnosis of achalasia was made, and peroral endoscopic myotomy was performed.

摘要

贲门失弛缓症是一种罕见的食管运动障碍性疾病,其特征为食管下括约肌不完全松弛以及食管体部无效收缩。这种疾病通常与肥胖无关;然而,近年来,已有减肥手术后发生贲门失弛缓症的病例报道。我们报告一例30岁女性患者,她在2018年接受了胃袖状切除术,术后4年出现吞咽困难、反流和体重减轻。诊断为贲门失弛缓症,并进行了经口内镜下肌切开术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/8c2438a646ea/ac9-12-e01584-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/0eb2432c63cd/ac9-12-e01584-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/831536553b11/ac9-12-e01584-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/42d4b75d64b8/ac9-12-e01584-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/0ee3cc173a2e/ac9-12-e01584-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/12c2fce62349/ac9-12-e01584-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/8c2438a646ea/ac9-12-e01584-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/0eb2432c63cd/ac9-12-e01584-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/831536553b11/ac9-12-e01584-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/42d4b75d64b8/ac9-12-e01584-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/0ee3cc173a2e/ac9-12-e01584-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/12c2fce62349/ac9-12-e01584-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/916d/11703431/8c2438a646ea/ac9-12-e01584-g006.jpg

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本文引用的文献

1
Peroral Endoscopic Myotomy for Achalasia after Bariatric Surgery: A Case Report and Review of the Literature.减重手术后贲门失弛缓症的经口内镜下肌切开术:病例报告及文献综述
Diagnostics (Basel). 2023 Oct 26;13(21):3311. doi: 10.3390/diagnostics13213311.
2
Surgical approaches for achalasia and obesity: a systematic review and patient-level meta-analysis.贲门失弛缓症和肥胖症的手术方法:系统评价和患者水平荟萃分析。
Langenbecks Arch Surg. 2023 Oct 16;408(1):403. doi: 10.1007/s00423-023-03143-5.
3
Outcomes of peroral endoscopic myotomy in patients with achalasia and prior bariatric surgery: A multicenter experience.
贲门失弛缓症患者及既往接受过减肥手术患者经口内镜下肌切开术的疗效:一项多中心经验。
Dis Esophagus. 2021 Dec 24;34(12). doi: 10.1093/dote/doab044.
4
Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0.高分辨率食管动力障碍:芝加哥分类版本 4.0。
Neurogastroenterol Motil. 2021 Jan;33(1):e14058. doi: 10.1111/nmo.14058.
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Efficacy and safety of peroral endoscopic myotomy after prior sleeve gastrectomy and gastric bypass surgery.既往接受袖状胃切除术和胃旁路手术后经口内镜下肌切开术的疗效和安全性。
World J Gastrointest Endosc. 2020 Dec 16;12(12):532-541. doi: 10.4253/wjge.v12.i12.532.
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Achalasia: physiology and diagnosis.贲门失弛缓症:生理学与诊断。
Ann N Y Acad Sci. 2020 Dec;1482(1):85-94. doi: 10.1111/nyas.14510. Epub 2020 Nov 2.
7
Achalasia after bariatric Roux-en-Y gastric bypass surgery reversal.减重手术后 Roux-en-Y 胃旁路术逆转后的贲门失弛缓症。
World J Gastroenterol. 2017 Oct 7;23(37):6902-6906. doi: 10.3748/wjg.v23.i37.6902.
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High prevalence of esophageal dysmotility in asymptomatic obese patients.无症状肥胖患者食管动力障碍的高发率。
Can J Gastroenterol Hepatol. 2014 Jun;28(6):311-4. doi: 10.1155/2014/960520.
9
Complexities of managing achalasia at a tertiary referral center: use of pneumatic dilatation, Heller myotomy, and botulinum toxin injection.三级转诊中心贲门失弛缓症的管理复杂性:气囊扩张、赫勒肌切开术及肉毒杆菌毒素注射的应用
Am J Gastroenterol. 2004 Jun;99(6):1029-36. doi: 10.1111/j.1572-0241.2004.30199.x.