• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肠系膜静脉血栓形成的并发症：杂合子因子V莱顿突变导致肠切除术后患者发生肺栓塞

Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post-Bowel Resection Surgery.

作者信息

Hamza Hafiz Muhammad, Malik Muhammad Muiz, Awan Ayaz Ahmed, Tariq Muhammad Daoud, Daoud Mohamed, Goyal Aman

机构信息

Department of Internal Medicine Foundation University Medical College Islamabad Pakistan.

Department of Internal Medicine Bogomolets National Medical University Kyiv Ukraine.

出版信息

Clin Case Rep. 2025 Jan 6;13(1):e70092. doi: 10.1002/ccr3.70092. eCollection 2025 Jan.

DOI:10.1002/ccr3.70092
PMID:39764273
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11702372/
Abstract

It is critical to recognize pulmonary embolism as soon as possible in patients who have gastrointestinal problems pre- and post-surgery. Even in the absence of conventional risk factors, the Factor V Leiden mutation emphasizes the importance of a thorough thrombophilia assessment. To effectively manage and prevent thrombotic episodes, prompt anticoagulant medication and genetic screening for family members are essential.

摘要

对于术前和术后有胃肠道问题的患者，尽快识别肺栓塞至关重要。即使没有传统的风险因素，凝血因子V莱顿突变也凸显了全面进行血栓形成倾向评估的重要性。为了有效管理和预防血栓形成事件，及时给予抗凝药物治疗以及对家庭成员进行基因筛查至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/4887a922d281/CCR3-13-e70092-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/8ebfabecae91/CCR3-13-e70092-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/89c5c5297fff/CCR3-13-e70092-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/47c4140b8137/CCR3-13-e70092-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/4887a922d281/CCR3-13-e70092-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/8ebfabecae91/CCR3-13-e70092-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/89c5c5297fff/CCR3-13-e70092-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/47c4140b8137/CCR3-13-e70092-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7901/11702372/4887a922d281/CCR3-13-e70092-g002.jpg

相似文献

1
Complications of Mesenteric Vein Thrombosis: Heterozygous Factor V Leiden Mutation Leads to Pulmonary Embolism in a Patient With Post-Bowel Resection Surgery.肠系膜静脉血栓形成的并发症：杂合子因子V莱顿突变导致肠切除术后患者发生肺栓塞
Clin Case Rep. 2025 Jan 6;13(1):e70092. doi: 10.1002/ccr3.70092. eCollection 2025 Jan.
2
Is the prevalence of the factor V Leiden mutation in patients with pulmonary embolism and deep vein thrombosis really different?肺栓塞和深静脉血栓形成患者中因子V莱顿突变的患病率真的不同吗？
Thromb Haemost. 1999 Mar;81(3):345-8.
3
Different risks of thrombosis in four coagulation defects associated with inherited thrombophilia: a study of 150 families.与遗传性易栓症相关的四种凝血缺陷中不同的血栓形成风险：一项对150个家庭的研究
Blood. 1998 Oct 1;92(7):2353-8.
4
Extensive Deep Vein Thrombosis and Pulmonary Embolism in a Young Patient With Heterozygous Factor V Leiden Mutation and Antiphospholipid Syndrome.一名患有杂合子因子V莱顿突变和抗磷脂综合征的年轻患者出现广泛深静脉血栓形成和肺栓塞
Cureus. 2024 Oct 26;16(10):e72425. doi: 10.7759/cureus.72425. eCollection 2024 Oct.
5
Small bowel varices secondary to chronic superior mesenteric vein thrombosis in a patient with heterozygous Factor V Leiden mutation: a case report.一名携带杂合子因子V莱顿突变的患者因慢性肠系膜上静脉血栓形成继发小肠静脉曲张：病例报告
J Med Case Rep. 2015 Oct 1;9:210. doi: 10.1186/s13256-015-0705-6.
6
Acute superior mesenteric vein thrombosis associated with factor V 'Leiden' gene mutation.与凝血因子V“莱顿”基因突变相关的急性肠系膜上静脉血栓形成
J Assoc Physicians India. 2003 Jun;51:611-3.
7
Factors V leiden and II 20210A in patients with symptomatic pulmonary embolism and deep vein thrombosis.有症状的肺栓塞和深静脉血栓形成患者中的凝血因子V莱顿突变和凝血因子II 20210A突变
Am J Med. 2001 Jan;110(1):12-5. doi: 10.1016/s0002-9343(00)00653-7.
8
Homozygous Factor V Leiden presenting as irreversible chronic colon ischemia resulting from inferior mesenteric vein thrombosis.杂合子因子 V Leiden 表现为不可逆的慢性结肠缺血，由肠系膜下静脉血栓形成引起。
Clin J Gastroenterol. 2021 Aug;14(4):1142-1146. doi: 10.1007/s12328-021-01440-4. Epub 2021 May 18.
9
Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen.携带第三代孕激素的口服避孕药所致深静脉血栓形成风险因凝血因子V莱顿突变而增加。
Lancet. 1995 Dec 16;346(8990):1593-6. doi: 10.1016/s0140-6736(95)91929-5.
10
Factor V Leiden thrombophilia.因子 V 莱顿血栓形成倾向。
Genet Med. 2011 Jan;13(1):1-16. doi: 10.1097/GIM.0b013e3181faa0f2.

本文引用的文献

1
The Magic of Proteases: From a Procoagulant and Anticoagulant Factor V to an Equitable Treatment of Its Inherited Deficiency.蛋白酶的魔力：从促凝和抗凝因子 V 到遗传性缺乏症的公平治疗。
Int J Mol Sci. 2023 Mar 26;24(7):6243. doi: 10.3390/ijms24076243.
2
Homozygous factor V leiden mutation: Rare etiology of pulmonary embolism.纯合子因子V莱顿突变：肺栓塞的罕见病因。
Ann Med Surg (Lond). 2022 Sep 13;82:104569. doi: 10.1016/j.amsu.2022.104569. eCollection 2022 Oct.
3
The prevalence of Factor V Leiden (Arg506Gln) mutation in King Khalid University Hospital patients, 2017-2019.
2017-2019 年，沙特国王哈立德大学医院患者中因子 V 莱顿（Arg506Gln）突变的流行率。
Nagoya J Med Sci. 2021 Aug;83(3):407-417. doi: 10.18999/nagjms.83.3.407.
4
Anticoagulation for Patients with Venous Thromboembolism: When is Extended Treatment Required?静脉血栓栓塞症患者的抗凝治疗：何时需要延长治疗？
TH Open. 2020 Dec 23;4(4):e446-e456. doi: 10.1055/s-0040-1721735. eCollection 2020 Oct.
5
Association between congenital thrombophilia and outcomes in pulmonary embolism patients.先天性血栓形成倾向与肺栓塞患者预后之间的关联。
Blood Adv. 2020 Dec 8;4(23):5958-5965. doi: 10.1182/bloodadvances.2020002955.
6
Colon Ischemia: An Update for Clinicians.结肠缺血：临床医生最新指南
Mayo Clin Proc. 2016 May;91(5):671-7. doi: 10.1016/j.mayocp.2016.02.006.
7
Review of the cost of venous thromboembolism.静脉血栓栓塞症成本综述。
Clinicoecon Outcomes Res. 2015 Aug 28;7:451-62. doi: 10.2147/CEOR.S85635. eCollection 2015.
8
Mesenteric venous thrombosis.肠系膜静脉血栓形成
J Clin Exp Hepatol. 2014 Sep;4(3):257-63. doi: 10.1016/j.jceh.2014.03.052. Epub 2014 Apr 13.
9
Risk factors for colon ischemia.结肠缺血的危险因素。
Am J Gastroenterol. 2004 Jul;99(7):1333-7. doi: 10.1111/j.1572-0241.2004.21436.x.
10
High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance).凝血因子V莱顿纯合子（活化蛋白C抵抗）患者发生血栓形成的风险很高。
Blood. 1995 Mar 15;85(6):1504-8.