Dimitrova Iva N, Simeonov Peyo
Department of Cardiology, University Hospital 'St. Ekaterina', Medical University of Sofia, Sofia, Bulgaria.
Front Cardiovasc Med. 2024 Dec 23;11:1441867. doi: 10.3389/fcvm.2024.1441867. eCollection 2024.
Formation of local type aortic aneurysm years after surgical repair of coarctation (CoA) occurs in 10% of patients independent of the surgical technique and is a potentially life-threatening condition if left untreated with a high risk of aortic rupture. Redo open surgery is associated with 14% in-hospital mortality and a high risk of complications. Endovascular treatment appears to be a feasible alternative with a high success rate and low morbidity and mortality, but data concerning long-term results is still mandatory. We describe the single center experience of a series of patients treated with endovascular stent grafting for large aneurysms after previous surgery for CoA.
This series involves 12 consecutive patients treated with endovascular stent grafting from April 2003 to January 2022 for late aneurysm at the site of previous surgical repair for CoA. Data on baseline characteristics, clinical, computed tomography (CT), procedural features, and in-hospital and long-term results were analyzed. All patients signed institutional informed consent for the procedure.
A total of 12 patients (average age 38.5 ± 10.2 years) underwent endovascular repair. The average interval between the initial surgical intervention and the aneurysm repair was 24.1 ± 9.1 years and the majority (83.3%) underwent synthetic patch aortoplasty as previous intervention. All patients were symptomatic at presentation with an average maximum diameter of the aneurysm 67.2 mm (ranging from 44 to 110 mm). Stent-graft placement was successful in all cases without procedural, in-hospital, 30-day, and one-year mortality or major complications. The average hospital stay was 9.3 days (range 7-19 days). For a mean follow-up period of 87 months (range, 23-168 months), all patients demonstrated positive aneurysm remodeling with cavity thrombosis and aneurysm diameter reduction to 54.9 mm (±16,6). For the entire follow-up period, we observed one aneurysm-related death and three deaths of heart failure.
Endovascular stent-graft treatment of patients with thoracic aneurysms after repair of CoA is an acceptable treatment of choice. It has shown promising results with high technical success and low immediate, short-and mid-term morbidity and mortality. Still, randomised control trials (RCTs) are needed to define the long-term outcome of this approach. Routine surveillance and screening of patients with previous CoA repair are mandatory.
缩窄性主动脉(CoA)手术修复多年后发生的局部型主动脉瘤,在10%的患者中出现,与手术技术无关,如果不治疗,是一种潜在的危及生命的疾病,有很高的主动脉破裂风险。再次进行开放手术的院内死亡率为14%,且并发症风险高。血管内治疗似乎是一种可行的替代方法,成功率高,发病率和死亡率低,但有关长期结果的数据仍然必不可少。我们描述了一系列曾因CoA接受手术治疗后出现大动脉瘤并接受血管内支架植入术的患者的单中心经验。
本系列包括2003年4月至2022年1月连续12例因CoA既往手术部位的晚期动脉瘤接受血管内支架植入术的患者。分析了基线特征、临床、计算机断层扫描(CT)、手术特征以及院内和长期结果的数据。所有患者均签署了该手术的机构知情同意书。
共有12例患者(平均年龄38.5±10.2岁)接受了血管内修复。初次手术干预与动脉瘤修复之间的平均间隔为24.1±9.1年,大多数患者(83.3%)之前接受过人工血管补片主动脉成形术。所有患者就诊时均有症状,动脉瘤平均最大直径为67.2mm(范围为44至110mm)。所有病例的支架植入均成功,无手术、院内、30天和1年死亡率或重大并发症。平均住院时间为9.3天(范围为7至19天)。平均随访期为87个月(范围为23至168个月),所有患者均显示动脉瘤呈阳性重塑,瘤腔内血栓形成,动脉瘤直径缩小至54.9mm(±16.6)。在整个随访期间,我们观察到1例与动脉瘤相关的死亡和3例心力衰竭死亡。
血管内支架植入术治疗CoA修复术后的胸主动脉瘤患者是一种可接受的治疗选择。它已显示出有前景的结果,技术成功率高,近期、短期和中期发病率和死亡率低。尽管如此,仍需要随机对照试验(RCT)来确定这种方法的长期结果。对既往有CoA修复史的患者进行常规监测和筛查是必要的。