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在可能感染情况下，带核细胞百分比与未成熟粒细胞百分比的比较 主要研究者

Comparison of Band Percentage vs Immature Granulocyte Percentage in the Setting of Possible Infection Principle Investigators.

作者信息

Hershberger Daniel, Samson Kaeli, Saeed M Ahsan

机构信息

Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Nebraska Medical Center, Omaha, Nebraska, USA.

Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, USA.

出版信息

Adv Hematol. 2024 Dec 30;2024:3616532. doi: 10.1155/ah/3616532. eCollection 2024.

DOI:10.1155/ah/3616532
PMID:39764354
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11703591/
Abstract

Sepsis is a major cause of mortality worldwide. Early identification and treatment are critical to improve survival. Band count has been used as part of SIRS criteria for the early identification of potentially septic patients. Unfortunately, band count requires manual interpretation. This leads to increased potential for intraobserver variability. Immature granulocytes are counted in an automated fashion, which has the potential to improve accuracy and reduce costs. We aim to compare the band percentage and immature granulocyte percentage to set the threshold for immature granulocyte percentage equal to the sensitivity of > 10% band count. A retrospective chart review was conducted at a single academic medical center. Data from patients with SIRS criteria and measured immature granulocyte and band percentages were utilized to explore potential associations between immature granulocyte percentages and band percentages. Data were analyzed using Spearman correlations, Wilcoxon rank-sum tests, and logistic regressions. We found no significant associations between immature granulocyte percentage and band percentage or other SIRS criteria. We conclude that immature granulocyte percentage does not correlate with band percentage in the setting of possible infection.

摘要

脓毒症是全球范围内主要的死亡原因。早期识别和治疗对于提高生存率至关重要。杆状核细胞计数已被用作全身炎症反应综合征（SIRS）标准的一部分，用于早期识别潜在的脓毒症患者。不幸的是，杆状核细胞计数需要人工解读。这导致观察者间变异性增加的可能性。未成熟粒细胞以自动化方式计数，这有可能提高准确性并降低成本。我们旨在比较杆状核细胞百分比和未成熟粒细胞百分比，以设定未成熟粒细胞百分比的阈值，使其等于杆状核细胞计数敏感性>10%时的阈值。在一家学术医疗中心进行了回顾性病历审查。利用符合SIRS标准且测量了未成熟粒细胞和杆状核细胞百分比的患者数据，探讨未成熟粒细胞百分比与杆状核细胞百分比之间的潜在关联。使用Spearman相关性分析、Wilcoxon秩和检验和逻辑回归分析数据。我们发现未成熟粒细胞百分比与杆状核细胞百分比或其他SIRS标准之间无显著关联。我们得出结论，在可能感染的情况下，未成熟粒细胞百分比与杆状核细胞百分比不相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/c1d06ffc190b/AH2024-3616532.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/c0e69c726d37/AH2024-3616532.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/4fe12e6b0e2a/AH2024-3616532.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/04826ecebf01/AH2024-3616532.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/c1d06ffc190b/AH2024-3616532.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/c0e69c726d37/AH2024-3616532.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/4fe12e6b0e2a/AH2024-3616532.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/04826ecebf01/AH2024-3616532.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de81/11703591/c1d06ffc190b/AH2024-3616532.004.jpg

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本文引用的文献

1
Evaluation of Immature Granulocyte Count as the Earliest Biomarker for Sepsis.评估未成熟粒细胞计数作为脓毒症的最早生物标志物
Indian J Crit Care Med. 2022 Feb;26(2):216-223. doi: 10.5005/jp-journals-10071-23920.
2
Immature granulocytes index as early marker of sepsis.不成熟粒细胞指数作为脓毒症的早期标志物。
Int J Lab Hematol. 2019 Jun;41(3):392-396. doi: 10.1111/ijlh.12990. Epub 2019 Feb 26.
3
Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients.
评估急诊科患者中乳酸、白细胞计数、中性粒细胞计数、降钙素原和未成熟粒细胞计数作为脓毒症生物标志物的情况。
Clin Biochem. 2017 Nov;50(16-17):956-958. doi: 10.1016/j.clinbiochem.2017.05.014. Epub 2017 May 25.
4
The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in patients with systemic inflammation.监测全身炎症患者未成熟中性粒细胞血水平的诊断和预后意义。
Crit Care. 2015 Feb 25;19(1):57. doi: 10.1186/s13054-015-0778-z.
5
Immature granulocytes predict microbial infection and its adverse sequelae in the intensive care unit.未成熟粒细胞可预测重症监护病房中的微生物感染及其不良后果。
J Crit Care. 2014 Aug;29(4):523-7. doi: 10.1016/j.jcrc.2014.03.033. Epub 2014 Apr 5.
6
Automated measurement of immature granulocytes: performance characteristics and utility in routine clinical practice.未成熟粒细胞的自动化检测：性能特征及在常规临床实践中的应用
Patholog Res Int. 2012;2012:483670. doi: 10.1155/2012/483670. Epub 2012 Feb 15.
7
Measurement of granulocyte maturation may improve the early diagnosis of the septic state.粒细胞成熟度的测量可能有助于提高脓毒症状态的早期诊断。
Clin Chem Lab Med. 2011 Sep 21;49(12):2089-95. doi: 10.1515/CCLM.2011.688.
8
Use of band cell percentage as an early predictor of death and ICU admission in severe acute pancreatitis.使用杆状核细胞百分比作为重症急性胰腺炎死亡和入住重症监护病房的早期预测指标。
Hepatogastroenterology. 2010 Nov-Dec;57(104):1543-8.
9
Is the band count useful in the diagnosis of infection? An accuracy study in critically ill patients.带计数在感染诊断中有用吗？一项危重症患者的准确性研究。
J Intensive Care Med. 2010 Nov-Dec;25(6):353-7. doi: 10.1177/0885066610377980. Epub 2010 Sep 13.
10
Clinical utility of the band count.分类计数的临床应用
Clin Lab Med. 2002 Mar;22(1):101-36. doi: 10.1016/s0272-2712(03)00069-6.