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生物样本库数字化:从数据采集到高效利用

Biobank Digitalization: From Data Acquisition to Efficient Use.

作者信息

Bukreeva Anastasiia S, Malsagova Kristina A, Petrovskiy Denis V, Butkova Tatiana V, Nakhod Valeriya I, Rudnev Vladimir R, Izotov Alexander A, Kaysheva Anna L

机构信息

Institute of Biomedical Chemistry, 109028 Moscow, Russia.

出版信息

Biology (Basel). 2024 Nov 22;13(12):957. doi: 10.3390/biology13120957.

DOI:10.3390/biology13120957
PMID:39765624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11726863/
Abstract

Biobanks are involved in a broad range of studies, including both basic and clinical research, so their functions and roles are evolving. Digital biobanks have emerged due to digitalization in this field; however, it also entails an increasing number of ethical and legal issues, in particular those related to the protection of donor data and potential commercial applications. The development of biobanks and the size of stored datasets lay the groundwork for proceeding to digital biobanks that intensely employ artificial intelligence tools. Digital biobanks can simplify the search for and access to biological specimens, thus contributing to the conduction of research and creating new collaborations. They are becoming an increasingly important tool for personalized medicine and an individualized approach to disease treatment, contributing to the elaboration of more accurate diagnostic methods and the development of innovative therapeutic strategies.

摘要

生物样本库参与广泛的研究,包括基础研究和临床研究,因此其功能和作用正在不断演变。由于该领域的数字化,数字生物样本库应运而生;然而,这也带来了越来越多的伦理和法律问题,特别是与捐赠者数据保护和潜在商业应用相关的问题。生物样本库的发展以及存储数据集的规模为深入应用人工智能工具的数字生物样本库奠定了基础。数字生物样本库可以简化生物样本的搜索和获取,从而有助于开展研究并建立新的合作关系。它们正日益成为个性化医疗和疾病个体化治疗方法的重要工具,有助于制定更准确的诊断方法和开发创新的治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/ed18959e893a/biology-13-00957-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/7dcae4b0976d/biology-13-00957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/5d2a45a9bd91/biology-13-00957-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/ed18959e893a/biology-13-00957-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/7dcae4b0976d/biology-13-00957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/5d2a45a9bd91/biology-13-00957-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45cf/11726863/ed18959e893a/biology-13-00957-g003.jpg

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