Chung Wai-Shan, Tang Ya-Chun, Cheung Yun-Chung
Division of Breast Surgery, Department of Surgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan.
Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Medical College of Chang Gung University, Taoyuan 33382, Taiwan.
Cancers (Basel). 2024 Dec 12;16(24):4143. doi: 10.3390/cancers16244143.
Contrast-enhanced mammography (CEM) uses intermittent dual-energy (low- and high-energy) exposures to produce low-energy mammograms and recombine enhanced images after the administration of iodized contrast medium, which provides more detailed information to detect breast cancers by using the features of morphology and abnormal uptake. In this article, we reviewed the literature to clarify the clinical applications of CEM, including (1) the fundamentals of CEM: the technique, radiation exposure, and image interpretation; (2) its clinical uses for cancer diagnosis, including problem-solving, palpable mass, suspicious microcalcification, architecture distortion, screening, and CEM-guided biopsy; and (3) the concerns of surgical oncology in pre-operative and neoadjuvant chemotherapy assessments. CEM undoubtedly plays an important role in clinical practice.
对比增强乳腺X线摄影（CEM）采用间歇性双能（低能和高能）曝光来生成低能乳腺X线照片，并在注射碘化造影剂后重组增强图像，通过形态学特征和异常摄取为检测乳腺癌提供更详细的信息。在本文中，我们回顾了文献以阐明CEM的临床应用，包括（1）CEM的基本原理：技术、辐射暴露和图像解读；（2）其在癌症诊断中的临床用途，包括解决问题、可触及肿块、可疑微钙化、结构扭曲、筛查以及CEM引导活检；（3）外科肿瘤学在术前和新辅助化疗评估中的关注点。CEM无疑在临床实践中发挥着重要作用。
