Kraus Karolina, Mikziński Paweł, Widelski Jarosław, Paluch Emil
Faculty of Medicine, Wroclaw Medical University, Wyb. Pasteura 1, 50-376 Wroclaw, Poland.
Department of Pharmacognosy with Medicinal Plants Garden, Lublin Medical University, 20-093 Lublin, Poland.
Antibiotics (Basel). 2024 Dec 1;13(12):1151. doi: 10.3390/antibiotics13121151.
Periprosthetic joint infections (PJIs) are a dangerous complication of joint replacement surgeries which have become much more common in recent years (mostly hip and knee replacement surgeries). Such a condition can lead to many health issues and often requires reoperation. Staphylococci is a bacterial group most common in terms of the pathogens causing PJIs. and coagulase-negative staphylococci are found in around two-thirds of PJI cases. Recently, the numbers of staphylococci that cause such infections and that are methicillin-resistant are increasing. This trend leads to difficulties in the treatment and prevention of such infections. That is why MRSA and MRSE groups require extraordinary attention when dealing with PJIs in order to successfully treat them. Controlling carriage, using optimal prosthetic materials, and implementing perioperative antimicrobial prophylaxis are crucial strategies in infection prevention and are as essential as quick diagnosis and effective targeted treatment. The comprehensive professional procedures presented in this review show how to deal with such cases.
人工关节周围感染（PJI）是关节置换手术的一种危险并发症，近年来这种手术变得越来越普遍（主要是髋关节和膝关节置换手术）。这种情况会导致许多健康问题，通常需要再次手术。葡萄球菌是引起PJI的病原体中最常见的细菌类别，凝固酶阴性葡萄球菌在约三分之二的PJI病例中被发现。最近，导致此类感染且耐甲氧西林的葡萄球菌数量正在增加。这种趋势给此类感染的治疗和预防带来了困难。这就是为什么在处理PJI时，耐甲氧西林金黄色葡萄球菌（MRSA）和耐甲氧西林表皮葡萄球菌（MRSE）群体需要格外关注，以便成功治疗它们。控制携带、使用最佳假体材料以及实施围手术期抗菌预防是预防感染的关键策略，与快速诊断和有效的靶向治疗同样重要。本综述中介绍的综合专业程序展示了如何处理此类病例。
