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三尖瓣狭窄。心房收缩期杂音、三尖瓣开放拍击音及右心房压力脉搏。

Tricuspid stenosis. Atrial systolic murmur, tricuspid opening snap, and right atrial pressure pulse.

作者信息

Wooley C F, Fontana M E, Kilman J W, Ryan J M

出版信息

Am J Med. 1985 Mar;78(3):375-84. doi: 10.1016/0002-9343(85)90327-4.

Abstract

Observations on the atrial systolic murmur, the tricuspid opening snap, and the right atrial pressure pulse of tricuspid stenosis are presented, based on catheter manometer intracardiac sound and pressure recordings in five patients with hemodynamically significant tricuspid stenosis. The manometer-recorded right atrial pressure pulse of tricuspid stenosis differed from the normal, with (1) elevation of right atrial pressure, (2) different morphologic features (tall, spiky A wave complete before C; small V wave with an interruption, the tricuspid opening snap notch at termination of the gradual Y descent; a diastolic plateau, the relatively flat diastolic segment of the right atrial pressure pulse following the tricuspid opening snap notch prior to the next A wave), and (3) the relative lack of right atrial pressure and right atrial pressure pulse response with normal respiration. The atrial systolic murmur, recorded in the right ventricular inflow tract, was complete by S1; the crescendo-decrescendo atrial systolic murmur configuration paralleled the right ventricular-right atrial diastolic pressure gradient at the time of the atrial A wave. The right atrial contraction-relaxation process, as reflected by the right atrial A wave ascent and descent, was complete at the onset of ventricular systole with P-R intervals of 170 to 200 msec. Thus, the timing and configuration of the atrial systolic murmur reflected the timing and completion of the right atrial contraction-relaxation process prior to the onset of right ventricular systole and the configuration of the tricuspid diastolic pressure gradient. The tricuspid opening snap was recorded in the right ventricular inflow tract and occurred at the time of a notch at the termination of the Y descent of the right atrial pressure pulse V wave, while right atrial pressure exceeded right ventricular pressure. The sound-pressure events were consistent with angiographic and echocardiographic studies, which showed doming or ballooning of the mobile, fused, stenotic tricuspid valve into the right ventricle during the Y descent of the right atrial pressure pulse. The tricuspid opening snap occurred at the time of the termination of the diastolic movement of the fused tricuspid unit into the right ventricle. These observations are presented within the framework of previous studies in order to trace the development of medical ideas about the pathophysiologic basis for the sound and pressure events of tricuspid stenosis.

摘要

基于对5例具有血流动力学意义的三尖瓣狭窄患者进行的心导管测压、心内声音及压力记录,对三尖瓣狭窄的心房收缩期杂音、三尖瓣开放拍击音及右心房压力脉搏进行了观察。测压记录的三尖瓣狭窄右心房压力脉搏与正常情况不同,表现为:(1)右心房压力升高;(2)形态特征不同(高大、尖锐的A波在C波之前完整;V波小且有中断,在逐渐下降的Y波终止处有三尖瓣开放拍击音切迹;舒张期平台,即紧跟三尖瓣开放拍击音切迹且在下一个A波之前的右心房压力脉搏相对平坦的舒张段);(3)正常呼吸时右心房压力及右心房压力脉搏反应相对缺乏。记录于右心室流入道的心房收缩期杂音在S1时完整;递增递减型心房收缩期杂音形态与心房A波时的右心室-右心房舒张期压力梯度平行。右心房A波的上升和下降所反映的右心房收缩-舒张过程在心室收缩开始时完成,P-R间期为170至200毫秒。因此,心房收缩期杂音的时间和形态反映了右心室收缩开始前右心房收缩-舒张过程的时间和完成情况以及三尖瓣舒张期压力梯度的形态。三尖瓣开放拍击音记录于右心室流入道,发生在右心房压力脉搏V波Y波下降终止处的切迹时,此时右心房压力超过右心室压力。声音-压力事件与血管造影和超声心动图研究一致,这些研究显示在右心房压力脉搏Y波下降期间,活动的、融合的、狭窄的三尖瓣呈圆顶状或气球样突入右心室。三尖瓣开放拍击音发生在融合的三尖瓣装置向右心室舒张期运动终止时。为了追溯关于三尖瓣狭窄声音和压力事件病理生理基础的医学观念的发展,在以往研究的框架内呈现了这些观察结果。

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