Tsang Hin-Fung, Leung Stanley W M, Hung Tin-Nok, Law Icy, Lam Ka-Wai, Chan Loiston, Wong Sze-Chuen Cesar
Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong SAR, China.
Department of Applied Biology & Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Diagnostics (Basel). 2024 Dec 20;14(24):2871. doi: 10.3390/diagnostics14242871.
(previously known as ) infection is not common in Hong Kong. is a fish-borne cestode parasite that infects humans after consuming raw or insufficiently cooked fish containing plerocercoids. We reported a case of infection in a 40-year-old woman who presented with a complaint of epigastric pain and diarrhea. A curvilinear opacity was seen at the upper quadrant of the abdomen via abdominal X-ray. An incomplete 80 cm long strobila of without a scolex and neck was found in her feces. A grayish-brown oval egg with an inconspicuous operculum and small knob at the abopercular end was also found. Species-level identification was performed using Nanopore sequencing. Complete blood count and serum vitamin B12 level were tested to check for megaloblastic anemia and vitamin B12 deficiency, respectively. Laboratory investigations demonstrated an elevated percentage of monocytes in peripheral blood. A single oral dose of praziquantel (25 mg/kg) was prescribed to the patient. There was no evidence of relapse after the treatment. We reported a case of infection using Oxford Nanopore NGS as a tool for accurate parasite identification.
（以前称为 ）感染在香港并不常见。 是一种通过鱼类传播的绦虫寄生虫，在食用含有裂头蚴的生鱼或未充分煮熟的鱼后会感染人类。我们报告了一例40岁女性感染 的病例，该患者主诉上腹部疼痛和腹泻。通过腹部X线检查，在腹部上象限可见一条曲线状不透光区。在她的粪便中发现了一条长80厘米、无头节和颈部的不完整链体。还发现了一个灰褐色椭圆形虫卵，其盖不明显，在反口端有一个小瘤。使用纳米孔测序进行种属鉴定。分别检测全血细胞计数和血清维生素B12水平，以检查是否存在巨幼细胞贫血和维生素B12缺乏。实验室检查显示外周血单核细胞百分比升高。给患者开了单剂量口服吡喹酮（25毫克/千克）。治疗后没有复发的迹象。我们报告了一例使用牛津纳米孔二代测序作为准确鉴定寄生虫工具的 感染病例。
