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用吡喹酮单剂量治疗人体日本裂头绦虫感染。

Single dose treatment with praziquantel for human Diphyllobothrium nihonkaiense infections.

作者信息

Ohnishi K, Murata M

机构信息

Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Japan.

出版信息

Trans R Soc Trop Med Hyg. 1993 Jul-Aug;87(4):482-3. doi: 10.1016/0035-9203(93)90049-v.

DOI:10.1016/0035-9203(93)90049-v
PMID:8249091
Abstract

Diphyllobothrium nihonkaiense is a large pseudophyllid cestode and one of the commonest parasites derived from fish in Japan. Three Japanese patients infected with D. nihonkaiense were treated with a single oral dose of 7, 23 or 25 mg/kg of praziquantel. All patients expelled the tapeworm with scolex, and no side effect was noted. This study indicates that single-dose treatment with praziquantel is effective against D. nihonkaiense infection.

摘要

日本裂头绦虫是一种大型假叶目绦虫,是日本最常见的鱼类源性寄生虫之一。三名感染日本裂头绦虫的日本患者接受了单次口服剂量为7、23或25mg/kg吡喹酮的治疗。所有患者均排出了带有头节的绦虫,且未观察到副作用。本研究表明,吡喹酮单剂量治疗对日本裂头绦虫感染有效。

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